Impact of HIV Self-Test Distribution to Male Partners of ANC Clients: Results of a Randomized Controlled Trial in Kenya.
Impact of HIV Self-Test Distribution to Male Partners of ANC Clients: Results of a Randomized Controlled Trial in Kenya.
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DOI：
10.1097/qai.0000000000001838
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发表时间：
2018-12-01
期刊：
影响因子：
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通讯作者：
Korte JE
中科院分区：
文献类型：
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作者：
Gichangi A;Wambua J;Mutwiwa S;Njogu R;Bazant E;Wamicwe J;Wafula R;Vrana CJ;Stevens DR;Mudany M;Korte JE
补充数字内容可在文本中获得。在肯尼亚，首次产前检查期间进行艾滋病毒检测是孕妇的标准做法。尽管非洲国家有一项促进男性伴侣检测的政策，但很少有男性伴侣陪同其伴侣进行艾滋病毒检测。我们评估了在肯尼亚ANC客户及其男性伴侣中使用口服艾滋病毒自我检测对艾滋病毒夫妇检测的影响。在肯尼亚东部和中部的一项三组随机对照研究中，同意参加第一次ANC访问的妇女被随机分配接受：(1)标准护理和标准信息卡；(2)改进说明男性艾滋病毒检测重要性的卡片；(3)口服艾滋病自检试剂盒2套及艾滋病检测资料。女性完成了基线和终点问卷调查，并在女性ANC客户登记后3个月对同意的男性伴侣进行了调查。主要结果是女性伴侣报告的艾滋病毒夫妇检测。我们随机抽取1410名首次接受ANC访问的女性，其中1215名成功随访。1333名男性合伙人同意了这项调查。在自我检测的研究组3中，79.1%（334/422）的妇女报告她们的伴侣作为夫妻的一部分进行了艾滋病毒检测，而研究组1和研究组2分别为27%（110/406）和35.1%（136/387）。90%以上使用口服艾滋病毒自检试剂盒的男性伴侣报告说，取样和阅读检测结果很容易。该研究表明，非洲人国民大会平台提供了一个独特的机会，通过女性伴侣分发自我检测，在男性中增加艾滋病毒夫妇检测。
Supplemental Digital Content is Available in the Text. In Kenya, HIV testing during first antenatal care (ANC) visit is a standard practice for pregnant women. Despite a policy promoting male partner testing in ANC, few male partners accompany their partners for HIV testing. We evaluated the impact of using oral HIV self-testing on HIV couples testing among ANC clients in Kenya and their male partners. In a 3-arm randomized control study in eastern and central Kenya, consenting women attending the first ANC visit were randomized to receive: (1) standard-of-care and a standard information card; (2) an improved card stating the importance of male HIV testing; and (3) 2 oral HIV self-test kits and HIV testing information. Women completed a baseline and endline questionnaire, and consenting male partners were surveyed 3 months after enrolling female ANC clients. The primary outcome was HIV couples testing as reported by the female partners. We randomized 1410 women at their first ANC visit of which 1215 were successfully followed up. One thousand one hundred thirty-three male partners consented to the survey. In the self-testing study arm 3, 79.1% (334/422) of the women reported that their partner tested for HIV as part of a couple, compared with 27% (110/406) and 35.1% (136/387) in study arm 1 and study arm 2, respectively. More than 90% of male partners who used the oral HIV self-test kits reported that it was easy to take sample and read the test results. The study demonstrates that the ANC platform offers a unique opportunity to increase HIV couples testing among men using self-testing through distribution by their female partners.