Intersubject synchronization of cortical activity during natural vision
Intersubject synchronization of cortical activity during natural vision
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DOI：
10.1126/science.1089506
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发表时间：
2004-03-12
期刊：
影响因子：
56.9
通讯作者：
Malach, R
中科院分区：
文献类型：
--
作者：
Hasson, U;Nir, Y;Malach, R
在自然条件下，所有的大脑在多大程度上都是一样的？我们通过让五名受试者在接受大脑功能成像的同时自由观看一部流行电影的半小时来探索这个问题。应用一个大脑的时空活动模式被用来模拟另一个大脑的活动的无偏分析，我们发现个体之间的体素-体素同步的惊人水平，不仅在主要和次要的视觉和听觉区域，而且在关联皮质。研究结果揭示了一个令人惊讶的趋势：在自然视觉过程中，个体大脑会“集体运转”。受试者之间的同步由广泛的皮质激活模式组成，这些模式与情绪唤醒场景和区域选择性成分相关。这些激活的特征是通过使用开放式的“反向相关”方法来揭示的，这种方法通过让大脑信号自己“挑选”每个特定皮质区域的最佳刺激来逆转传统的分析。
To what extent do all brains work alike during natural conditions? We explored this question by letting Five subjects freely view half an hour of a popular movie while undergoing functional brain imaging. Applying an unbiased analysis in which spatiotemporal activity patterns in one brain were used to "model" activity in another brain, we found a striking level of voxel-by-voxel synchronization between individuals, not only in primary and secondary visual and auditory areas but also in association cortices. The results reveal a surprising tendency of individual brains to "tick collectively" during natural vision. The intersubject synchronization consisted of a widespread cortical activation pattern correlated with emotionally arousing scenes and regionally selective components. The characteristics of these activations were revealed with the use of an open-ended "reverse-correlation" approach, which inverts the conventional analysis by letting the brain signals themselves "pick up" the optimal stimuli for each specialized cortical area.