Effects of both Sr and Mg substitution on compositions of biphasic calcium phosphate derived from hydrothermal method
Effects of both Sr and Mg substitution on compositions of biphasic calcium phosphate derived from hydrothermal method
复制标题
Sr和Mg同时取代对水热法双相磷酸钙成分的影响
DOI：
10.1111/ijac.12771
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发表时间：
2018
影响因子：
2.1
通讯作者：
Yang Xianjin
中科院分区：
文献类型：
--
作者：
Xu Yiming;Geng Zhen;Gao Zhonghui;Zhuo Xianglong;Li Bing;Cui Zhenduo;Zhu Shengli;Liang Yanqin;Li Zhaoyang;Yang Xianjin
双相磷酸钙（BCP）陶瓷是生物材料领域的研究热点。调控BCP的相组成对提高其生物活性至关重要。本研究采用传统的水热法制备BCP陶瓷，深入研究了Sr和Mg的添加对BCP陶瓷相组成和形貌的影响。结果表明，Sr和Mg的加入均促进了β-TCP的生成，且在pH值为8.5和10.5时，Sr和Mg的加入量与β-TCP相对含量的关系相似。β-TCP相的相对含量随Sr的加入量线性增加。β-TCP相对含量随Mg添加量的增加呈二次曲线变化，当Mg添加量达到30%时，β-TCP相对含量达到峰值。此外，当取代度相同时，pH值为8.5时合成的样品中β-TCP相的含量高于pH值为10.5时合成的样品。在Sr取代的样品中，形态没有显著变化，而在Mg取代的样品中，观察到Mg的加入使密度增加。这些结果和发现为通过改变Mg和Sr的初始取代来控制BCP的相组成提供了更全面的知识。
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Biphasic calcium phosphate (BCP) ceramics have received much attention in the field of biomaterials. Regulation of phase compositions of BCP is extremely important for improving their bioactivity. In this study, the effects of Sr- and Mg-addition on the phase composition and morphology of BCP ceramics, prepared by a conventional hydrothermal way, were investigated deeply. The results indicated that the addition of Sr and Mg both facilitated the generation of β-TCP, and the relationships between the addition and the relative content of β-TCP under different pH 8.5 and 10.5 were similar. The relative content of β-TCP phase increased linearly with the Sr addition. Meantime, the relative content of β-TCP changed quadratically with the Mg addition and reached its peak when the Mg addition was up to 30%. Besides, the fraction of β-TCP phase of samples synthesized at pH 8.5 was higher than that of samples synthesized at pH 10.5 when the substitution was same. The morphology did not change significantly in Sr-substituted samples while an enhancement in density was observed with Mg addition in Mg-substituted samples. These results and findings provide more comprehensive knowledge about controlling the phase compositions of BCP by changing the initial substitution of Mg and Sr.
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