Malignant ascites as a manifestation of advanced papillary renal cell cancer (pRCC).
Malignant ascites as a manifestation of advanced papillary renal cell cancer (pRCC).
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恶性腹水是晚期乳头状肾细胞癌 (pRCC) 的表现。
DOI：
10.1200/jco.2015.33.7_suppl.465
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发表时间：
2015
影响因子：
45.3
通讯作者：
R. Srinivasan
中科院分区：
文献类型：
--
作者：
J. Friend;D. Su;Rashmi Thimmapuram;James Peterson;G. Hawks;M. Ninos;W. Linehan;R. Srinivasan
465背景：腹膜癌病和腹水是常见的和临床上具有挑战性的并发症与几种恶性肿瘤，如卵巢癌。虽然晚期肾细胞癌（RCC）患者很少报告腹水，但其真实发生率，特别是在非透明细胞变异中，仍然不清楚。在这里，我们描述了pRCC患者腹水的发生率和临床特征。研究方法：在对我们的临床数据库进行回顾时，确定了在NCI泌尿肿瘤分支就诊的转移性肾细胞癌（RCC）患者。评价了放射学和/或细胞学明显腹水的发生率、相关临床特征和生存率，以及同期透明细胞RCC（ccRCC）队列中腹水的发生率。结果：2002年至2014年期间共观察到241例转移性RCC患者，其中pRCC 109例，ccRCC 125例。17例转移性pRCC患者（17/109，15.5%）有明显的肿瘤转移。
465 Background: Peritoneal carcinomatosis and ascites are frequent and clinically challenging complications associated with several malignancies such as ovarian cancer. Although ascites is rarely reported in patients with advanced renal cell carcinoma (RCC), its true incidence, particularly in non-clear cell variants, remains poorly defined. Here, we describe the incidence of and clinical characteristics associated with ascites in patients with pRCC. Methods: Patients with metastatic renal cell carcinoma (RCC) seen at the NCI Urologic Oncology Branch were identified in a review of our clinical database. The incidence of radiologically and/or cytologically evident ascites, relevant associated clinical characteristics, and survival were evaluated as was the incidence of ascites in a contemporaneous clear cell RCC (ccRCC) cohort. Results: 241 patients with metastatic RCC were seen between 2002 and 2014, including 109 with pRCC and 125 with ccRCC. Seventeen patients with metastatic pRCC (17/109,15.5%) had evi...