Immune functions of cord blood cells before and after transplantation.
Immune functions of cord blood cells before and after transplantation.
复制标题
脐带血细胞移植前后的免疫功能。
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
J. Wagner
中科院分区：
文献类型：
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作者：
M. Roncarolo;M. Roncarolo;M. Bigler;S. Martino;E. Ciuti;P. Tovo;J. Wagner
有大量报告表明，接受 HLA 匹配或 HLA 不同脐带移植的患者的急性和慢性移植物抗宿主病有所减少。有人提出，这可能是由于新生儿免疫系统的独特特性，它允许对同种抗原产生耐受性。这篇综述讨论了对比脐带血细胞和外周血细胞免疫功能的实验证据。
There have been numerous reports of decreased acute and chronic graft-versus-host disease in patients receiving HLA-matched or HLA-disparate umbilical cord transplants. It has been proposed that this may be due to the unique properties of the neonatal immune system, which permit the development of tolerance to alloantigens. This review discusses experimental evidence contrasting the immune functions of cells derived from cord blood and those from peripheral blood.