Global cognitive scores do not predict outcome after subthalamic nucleus deep brain stimulation.
Global cognitive scores do not predict outcome after subthalamic nucleus deep brain stimulation.
复制标题
DOI：
10.1002/mds.26292
复制
发表时间：
2015-08
期刊：
影响因子：
--
通讯作者：
Machado AG
中科院分区：
文献类型：
--
作者：
Floden D;Busch RM;Cooper SE;Kubu CS;Machado AG
痴呆症是 DBS 治疗帕金森病的禁忌症。最近的证据表明，使用常见筛查方法（马蒂斯痴呆评定量表）测量的边缘认知功能对 STN DBS 后的生活质量 (QoL) 产生负面影响。我们试图在更大范围的具有更广泛的术前整体认知表现的患者中复制和扩展这一发现。我们的数据表明，筛查措施的表现与生活质量或医疗结果无关，即使分数远低于识别痴呆症的临界值。这种认知筛查方法缺乏足够的敏感性，无法保证其用于预测哪些患者将从 DBS 中获得生活质量获益。
Presence of dementia is a contraindication for DBS treatment of Parkinson’s disease. Recent evidence suggests that borderline cognitive function, as measured with a common screening measure, the Mattis Dementia Rating Scale, has a negative impact on quality of life (QoL) after DBS of the STN. We attempted to replicate and extend this finding in a larger group of patients with a wider range of preoperative global cognitive performance. Our data indicate that performance on the screening measure is not associated with QoL or medical outcomes, even with scores well below the cutoff for identifying dementia. This cognitive screening measure lacks sufficient sensitivity to warrant its use in predicting which patients will show QoL benefit from DBS.
登录
查看更多内容
影响因子：
9.9
作者：
Green, J;McDonald, WM;DeLong, MR
通讯作者：
DeLong, MR
影响因子：
8.6
作者：
Litvan, Irene;Goldman, Jennifer G.;Troester, Alexander I.;Schmand, Ben A.;Weintraub, Daniel;Petersen, Ronald C.;Mollenhauer, Brit;Adler, Charles H.;Marder, Karen;Williams-Gray, Caroline H.;Aarsland, Dag;Kulisevsky, Jaime;Rodriguez-Oroz, Maria C.;Burn, David J.;Barker, Roger A.;Emre, Murat
通讯作者：
Emre, Murat
影响因子：
4.4
作者：
Witt, Karsten;Daniels, Christine;Deuschl, Guenther
通讯作者：
Deuschl, Guenther
影响因子：
4
作者：
Abboud, Hesham;Mehanna, Raja;Fernandez, Hubert H.
通讯作者：
Fernandez, Hubert H.
影响因子：
8.6
作者：
Daniels, Christine;Krack, Paul;Witt, Karsten
通讯作者：
Witt, Karsten