Analytical reconstruction of 4D dynamic cardiac SPECT with noise-reduction and non-uniform attenuation compensation.

Analytical reconstruction of 4D dynamic cardiac SPECT with noise-reduction and non-uniform attenuation compensation.
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通过降噪和非均匀衰减补偿对 4D 动态心脏 SPECT 进行分析重建。

DOI:
10.1016/j.nima.2006.10.061
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发表时间:
2007
期刊:
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment
影响因子:
--
通讯作者:
Liang,Zhengrong
Liang,Zhengrong
中科院分区:
--
文献类型:
--
作者:
Fan,Yi;Lu,Hongbing;Hao,Chongyang;Liang,Zhengrong

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本研究的重点是心脏动态SPECT的定量重建。材料与方法首先将Karhunen-Loeve (KL)变换应用于门控帧或正弦图数据,沿时间方向去相关动态信息。然后,通过惩罚加权最小二乘最小化处理泊松噪声,然后通过诺维科夫公式对处理后的正弦图进行衰减补偿的解析反演。重构是通过逆KL变换完成的。结果在模拟人体躯干的NCAT模型上模拟了动态或门控心脏图,与传统逐帧重建方法相比,该方法的重建效果有显著改善。结论动态SPECT的分析重建方法一致、高效,具有较好的应用前景。
BACKGROUNDThis study focuses on quantitative reconstruction of dynamic cardiac SPECT.MATERIAL AND METHODSThe Karhunen–Loeve (KL) transform is first applied to gated frames or sinogram data to de-correlate the dynamic information along the time direction. Then the Poisson noise is treated by a penalized weighted least-squares minimization, followed by an analytical inversion of the treated sinograms with attenuation compensation via the Novikov formula. The reconstruction is completed by inverse KL transform.RESULTSDynamic or gated cardiac sinograms were simulated from the NCAT phantom mimicking the human torso, and their reconstructions by the presented method showed significant improvement over the conventional methods of frame-by-frame reconstruction.CONCLUSIONThis analytical reconstruction of dynamic SPECT is consistent and efficient with a good potential for practical use.
一种基于理论的预重构滤波器,用于门控心脏 SPECT 中的时空降噪
DOI: 10.1109/nssmic.2000.950083
发表时间: 2000
期刊: 2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149)
影响因子: --
作者:
Hongbing Lu;G. Han;Dongqing Chen;Lihong C. Li;Zhengrong Liang
通讯作者: Zhengrong Liang