Registration error of the liver CT using deformable image registration of MIM Maestro and Velocity AI.
Registration error of the liver CT using deformable image registration of MIM Maestro and Velocity AI.
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DOI：
10.1186/s12880-017-0202-z
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发表时间：
2017-05-04
影响因子：
2.7
通讯作者：
Sakurai H
中科院分区：
文献类型：
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作者：
Fukumitsu N;Nitta K;Terunuma T;Okumura T;Numajiri H;Oshiro Y;Ohnishi K;Mizumoto M;Aihara T;Ishikawa H;Tsuboi K;Sakurai H
正确了解照射面积和剂量对于照射后变形的器官（例如肝脏）的再照射非常重要。我们使用可变形图像配准（DIR）软件产品MIM Maestro（MIM）和Velocity AI（Velocity）研究了空间配准误差。对 24 名肝脏肿瘤患者进行治疗前计算机断层扫描 (CT) 和治疗后 CT 的图像配准。所有患者均接受质子束治疗，随访时间为4-14个月（中位10个月）。我们对治疗前 CT 进行了 DIR，并通过计算金属标记物（靠近肿瘤植入）的错位将其与治疗后 CT 进行比较。两种产品的基准配准误差相当：MIM 为 0.4–32.9 (9.3±±9.9) mm，Velocity 为 0.5–38.6 (11.0±±10.0) mm，并且与 MIM 的肿瘤直径相关 (r = 0.69，P = 0.002) 和 Velocity (r = 0.68，P = 0.0003)。就增强效果而言，MIM 的基准配准误差为 1.0–24.9 (7.4±±7.7) mm，Velocity 的基准配准误差为 0.3–29.6 (8.9±±7.2) mm，比平扫 CT 的基准配准误差短（两者的 P = 0.04）。 MIM 和 Velocity 的 DIR 性能与肝脏相当。 DIR 的基准配准误差取决于肿瘤直径。此外，对比增强 CT 提高了 MIM 和 Velocity 的准确性。 H28-102； 2016年7月14日批准。
Understanding the irradiated area and dose correctly is important for the reirradiation of organs that deform after irradiation, such as the liver. We investigated the spatial registration error using the deformable image registration (DIR) software products MIM Maestro (MIM) and Velocity AI (Velocity). Image registration of pretreatment computed tomography (CT) and posttreatment CT was performed in 24 patients with liver tumors. All the patients received proton beam therapy, and the follow-up period was 4–14 (median: 10) months. We performed DIR of the pretreatment CT and compared it with that of the posttreatment CT by calculating the dislocation of metallic markers (implanted close to the tumors). The fiducial registration error was comparable in both products: 0.4–32.9 (9.3 ± 9.9) mm for MIM and 0.5–38.6 (11.0 ± 10.0) mm for Velocity, and correlated with the tumor diameter for MIM (r = 0.69, P = 0.002) and for Velocity (r = 0.68, P = 0.0003). Regarding the enhancement effect, the fiducial registration error was 1.0–24.9 (7.4 ± 7.7) mm for MIM and 0.3–29.6 (8.9 ± 7.2) mm for Velocity, which is shorter than that of plain CT (P = 0.04, for both). The DIR performance of both MIM and Velocity is comparable with regard to the liver. The fiducial registration error of DIR depends on the tumor diameter. Furthermore, contrast-enhanced CT improves the accuracy of both MIM and Velocity. H28-102; July 14, 2016 approved.