Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells
Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells
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DOI：
10.1039/b903388b
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发表时间：
2009-01-01
期刊：
影响因子：
6.1
通讯作者：
Nagasaki, Yukio
中科院分区：
文献类型：
--
作者：
Kojima, Ryota;Yoshimoto, Keitaro;Nagasaki, Yukio
在PEG-凝胶微图案化表面上构建了包含各种未成熟细胞的胎鼠肝细胞的球体阵列，并且通过与作为饲养细胞的非实质肝细胞共培养，其肝活性和分化诱导程度显著上调。
A spheroid array of fetal mouse liver cells, which comprise various immature cells, was constructed on a PEG-gel micropatterned surface and its hepatic activity and degree of differentiation induction were significantly upregulated by co-culture with nonparenchymal liver cells as feeder-cells.