Completion of axillary dissection for a positive sentinel node: necessary or not?

Completion of axillary dissection for a positive sentinel node: necessary or not?
复制标题

DOI:
10.1007/s11912-009-0004-8
复制
发表时间:
2009-01
影响因子:
4.7
通讯作者:
Julian, Thomas B.
Julian, Thomas B.
中科院分区:
医学2区
文献类型:
--
作者:
Erb, Kathleen M.;Julian, Thomas B.

文献摘要

参考文献

被引文献

相似文献

前哨淋巴结切除已被广泛接受为评估腋窝转移性乳腺癌的初始外科步骤。当结节呈阳性时,标准的护理是完成腋下结节清扫术,这是一种更长时间的手术,具有更高的发病率。本文综述了前哨淋巴结试验的数据、在前哨淋巴结阳性的情况下不进行腋窝淋巴结清扫的病例系列报道、预测非前哨淋巴结状态的模型以及与腋窝手术相关的发病率。尽管假阴性率约为10%,但早期结果表明,单纯前哨淋巴结切除后局部复发率要低得多,全身治疗可能会使腋窝绝育。在选定的患者中,放弃腋窝淋巴结清扫可能是合适的,尽管没有随机的临床试验数据来支持或驳斥这一建议。
Sentinel node excision has been widely accepted as the initial surgical step for evaluating the axilla for metastatic breast cancer. When the nodes are positive, the standard of care is to complete the axillary node dissection, a more extended procedure that carries an increased risk for morbidity. This article reviews data from sentinel lymph node trials, case series reports of outcomes when axillary node dissection was not performed in the setting of positive sentinel nodes, models for predicting the status of nonsentinel nodes, and the morbidity associated with axillary operations. Despite an approximate 10% false-negative rate, early results indicate that there is a much lower local recurrence rate after sentinel node excision alone and that systemic therapy may sterilize the axilla. In selected patients, it may be appropriate to forgo an axillary node dissection, although there are no randomized clinical trial data to support or refute this suggestion.
DOI: 10.1245/aso.2005.09.007
发表时间: 2005-09-01
影响因子: 3.7
作者:
Khan, A;Sabel, MS;Newman, LA
通讯作者: Newman, LA
DOI: 10.2325/jbcs.14.16
发表时间: 2007-01-01
期刊: Breast cancer (Tokyo, Japan)
影响因子: --
作者:
Takei, Hiroyuki;Suemasu, Kimito;Tabei, Toshio
通讯作者: Tabei, Toshio
DOI: 10.1245/aso.2003.03.015
发表时间: 2003-12-01
影响因子: 3.7
作者:
Van Zee, KJ;Manasseh, DME;Kattan, MW
通讯作者: Kattan, MW
DOI: 10.1097/sla.0b013e318153ff40
发表时间: 2008-01-01
期刊: ANNALS OF SURGERY
影响因子: 9
作者:
Bergkvist, Leif;de Boniface, Jana;Frisell, Jan
通讯作者: Frisell, Jan
DOI: 10.1245/s10434-007-9403-y
发表时间: 2007-10-01
影响因子: 3.7
作者:
Newman, Erika A.;Sabel, Michael S.;Newman, Lisa A.
通讯作者: Newman, Lisa A.