Asymmetry between salivary cortisol and α-amylase reactivity to stress:: Relation to aggressive behavior in adolescents
Asymmetry between salivary cortisol and α-amylase reactivity to stress:: Relation to aggressive behavior in adolescents
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DOI：
10.1016/j.psyneuen.2006.05.010
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发表时间：
2006-09-01
影响因子：
3.7
通讯作者：
Trickett, Penelope K.
中科院分区：
文献类型：
--
作者：
Gordis, Elana B.;Granger, Douglas A.;Trickett, Penelope K.
这项研究使用多生理系统测量方法来检验这一假设，即应激心理生物学的主要组成部分之间的不对称与青年的非典型行为有关[Bauer，A.M.，Quas，J.A.，Boyce，W.T.，2002。生理反应与儿童行为之间的联系：多系统方法的优势。J.Dev.行为。佩迪亚特。23、102-113]。青少年(N=67；年龄10-14岁；52%男性)在改良的Trier社会压力测试(TSST，Kirschbaum，C.，Pirke，K.，Hellhamm，D.H.，1993)之前提供了2份唾液样本，并在修订后提供了4份样本。“特里尔社会压力测试”：一种在实验室环境中调查心理生物压力反应的工具。神经心理生物学28，76-81)。对样本进行皮质醇(C)和α-淀粉酶(A-A)检测，后者是交感神经系统(SNS)活性的替代标记物。父母/监护人和青少年报告了青少年的攻击行为。唾液A-A和C均随TSST的增加而增加，其中A-A在TSST后即刻达到峰值，C在TSST后10min达到峰值。用曲线下面积(AUC)评价A-A和C应激反应。不对称的C和A-A反应性解释了父母报告的青少年攻击性差异的7%。在较低的A-A反应性水平上，较低的C反应性对应较高的攻击性等级，但在较高的A-A反应性水平上，C反应性与攻击性无关。这些结果支持了Bauer et at的假设。并强调多系统测量方法在青少年攻击性的生物社会模型中的重要性。(C)2006爱思唯尔有限公司。保留所有权利。
This study used a multiple physiological systems measurement approach to test the hypothesis that asymmetry between the major components of the psychobiology of stress is associated with atypical behavior in youth [Bauer, A.M., Quas, J.A., Boyce, W.T., 2002. Associations between physiological reactivity and children's behavior: advantages of a multisystem approach. J. Dev. Behav. Pediatr. 23, 102-113]. Adolescents (N = 67; ages 10-14; 52% male) provided 2 saliva samples before, and 4 samples after, a modified Trier Social Stress Test (TSST, Kirschbaum, C., Pirke, K., Hellhammer, D.H., 1993. The "Trier Social Stress Test": a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28, 76-81). Samples were assayed for cortisol (C) and alpha-amytase (A-A), a surrogate marker of sympathetic nervous system (SNS) activity. Parents/ guardians and adolescents reported on adolescents' aggressive behavior. Both salivary A-A and C increased in response to the TSST, with a peak response for A-A immediately post-TSST and for C 10 min post-TSST. A-A and C stress reactivity were estimated using area under the curve (AUC). Asymmetrical C and A-A reactivity accounted for 7% of the variance in parent-reported adolescent aggression. At lower Levels of A-A reactivity, lower C reactivity corresponded to higher aggression ratings, but at high A-A reactivity levels, C reactivity was not related to aggression. These results support the hypothesis of Bauer et at. and underscore the importance of a multiple systems measurement approach in biosocial models of adolescent aggression. (c) 2006 Elsevier Ltd. All rights reserved.