The relationship of primary tumor thickness in carcinoma of the tongue to subsequent lymph node metastasis.
The relationship of primary tumor thickness in carcinoma of the tongue to subsequent lymph node metastasis.
复制标题
舌癌原发肿瘤厚度与后续淋巴结转移的关系。
DOI：
10.1038/sj/dmfr/4600615
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
K. Katsura
中科院分区：
文献类型：
--
作者：
T. Hayashi;J. Ito;S. Taira;K. Katsura
目标
目的探讨I/II期舌癌原发灶厚度是否能提供淋巴结转移的信息。
方法
20例T1 N 0 M0或T2 N 0 M0舌癌患者进行了研究。原发性肿瘤厚度测量后对比螺旋计算机断层扫描或口腔内超声检查。每隔2-4周用超声检查定期评估颈部淋巴结。计算了随后转移的敏感性、特异性和准确性。
结果
在随访期间，9例患者的9个淋巴结出现阳性超声检查结果。11名患者接受了颈部清扫术，9名患者的组织病理学阳性淋巴结。在最短20个月的随访期内，9例患者的超声检查没有发现转移。原发肿瘤厚度3-16 mm，以5 mm为界值，诊断淋巴结转移的敏感性、特异性和准确性分别为64%、100%和75%。
结论
厚度大于5 mm的I/II期舌癌患者更容易发生淋巴结转移。
OBJECTIVES
To study whether primary tumor thickness of stage I/II tongue carcinoma provides information about subsequent lymph node metastasis.
METHODS
Twenty consecutive patients with T1N0M0 or T2N0M0 tongue carcinoma were studied. Primary tumor thickness was measured with post-contrast helical computed tomography or intra-oral sonography. Cervical lymph nodes were evaluated periodically with sonography at intervals of 2-4 weeks. Sensitivity, specificity and accuracy for subsequent metastasis was calculated.
RESULTS
Positive sonographic findings appeared in nine nodes of nine patients during this follow-up period. Eleven patients underwent neck dissections, and nine had histopathologically positive nodes. Nine patients had no sonographic findings of metastasis during a minimum follow-up period of 20 months. Primary tumor thickness varied from 3-16 mm. Using 5 mm as a cut-off thickness, the sensitivity, specificity and accuracy for subsequent lymph node metastasis were 64, 100 and 75% respectively.
CONCLUSIONS
Patients with stage I/II tongue carcinoma which is more than 5 mm thick are more likely to develop lymph node metastasis.
DOI：
10.1002/(sici)1097-0347(199803)20:2
发表时间：
1998-03-01
影响因子：
2.9
作者：
Byers, RM;El-Naggar, AK;Wolf, PJ
通讯作者：
Wolf, PJ