Consumption of 100% Fruit Juice and Risk of Obesity and Metabolic Syndrome: Findings from the National Health and Nutrition Examination Survey 1999-2004
Consumption of 100% Fruit Juice and Risk of Obesity and Metabolic Syndrome: Findings from the National Health and Nutrition Examination Survey 1999-2004
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DOI：
10.1080/07315724.2010.10719901
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发表时间：
2010-12-01
影响因子：
3.5
通讯作者：
Fulgoni, Victor L., III
中科院分区：
文献类型：
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作者：
Pereira, Mark A.;Fulgoni, Victor L., III
目的：添加糖对健康的影响受到了广泛的关注，但很少有研究调查天然含糖食物（如100%果汁）与肥胖和相关疾病风险之间的关系。因此，我们的目的是在美国人群的代表性样本中研究100%果汁摄入量与肥胖和代谢综合征风险之间的关系。方法：对1999-2004年国家健康和营养调查中的多种族美国成年人样本进行了横断面分析，以检查100%果汁消费量与肥胖（体重指数[BMI] >= 30 kg/m2）和代谢综合征（成人治疗小组[ATP]定义不佳）的几率。我们使用逻辑回归分析来估计每类果汁消费暴露的肥胖和代谢综合征的几率，同时调整协变量，可能是这种association.Results的混杂因素：14,196名成年人包括在样本中，3961是果汁消费者。与非消费者相比，100%果汁消费者的平均BMI、腰围和胰岛素抵抗的稳态模型评估（HOMA）较低（p < 0.001）。摄入水平（oz/d）与HOMA呈线性负相关（p < 0.001），而与BMI和腰围呈U形相关（p < 0.001）。与非消费者相比，消费者肥胖的几率低22%（95%置信区间[CI] = 13%-30%），代谢综合征的几率低15%（95% CI = 10%-28%）。调整人口统计学和生活方式因素后，肥胖的几率较低，仍然具有统计学意义，但在统计学上显着降低代谢综合征的几率不再noted.Conclusions：与nonconsumers相比，那些谁消耗100%果汁瘦，胰岛素敏感性更高，肥胖和代谢综合征的几率较低。与代谢综合征的关联主要由其他生活方式因素解释，而与肥胖的关联仍然是独立的。需要进行实验研究，以确定饮用100%果汁与降低肥胖和代谢综合征风险之间是否存在任何直接的生理联系。
Objectives: The health effects of added sugars have received much attention, but few studies have examined the association between foods that naturally contain sugar, such as 100% fruit juice, and risk of obesity and related conditions. Therefore, our purpose was to study the association between 100% fruit juice intake and risk of obesity and metabolic syndrome in a representative sample of the U.S. population.Methods: Cross-sectional analysis of a multiethnic sample of U.S. adults from the National Health and Nutrition Examination Survey 1999-2004 was undertaken to examine the association between 100% fruit juice consumption and the odds of obesity (body mass index [BMI] >= 30 kg/m(2)) and metabolic syndrome (Adult Treatment Panel [ATP] ill definition). We used logistic regression analysis to estimate the odds of obesity and metabolic syndrome per category of fruit juice consumption exposure, while adjusting for covariates that may be confounders of this association.Results: Of 14,196 adults included in the sample, 3961 were consumers of fruit juice. Consumers of 100% fruit juice, relative to nonconsumers, had lower mean BMI, lower waist circumference, and lower homeostasis model assessment (HOMA) insulin resistance (p < 0.001). Level of intake (oz/d) had a linear inverse association with HOMA (p < 0.001), whereas the association with BMI and waist circumference was U-shaped (p < 0.001). Consumers relative to nonconsumers had 22% (95% confidence interval [CI] = 13%-30%) lower odds of obesity and 15% (95% CI = 10%-28%) lower odds of metabolic syndrome. After adjustment for demographics and lifestyle factors, the lower odds of obesity remained statistically significant, but a statistically significant reduction in odds of metabolic syndrome was no longer noted.Conclusions: Compared with nonconsumers, those who consumed 100% fruit juice were leaner, were more insulin sensitive, and had lower odds of obesity and metabolic syndrome. The association with metabolic syndrome was explained primarily by other lifestyle factors, while the association with obesity remained independent. Experimental studies are needed to determine whether any direct physiologic link exists between consumption of 100% fruit juice and lower risks for obesity and metabolic syndrome.