Native and foreign born as predictors of pediatric asthma in an Asian immigrant population: a cross sectional survey.
Native and foreign born as predictors of pediatric asthma in an Asian immigrant population: a cross sectional survey.
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在亚洲移民人口中，本地人和外国作为儿科哮喘的预测因素：横断面调查。
DOI：
10.1186/1476-069x-6-13
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发表时间：
2007-05-02
影响因子：
6
通讯作者：
Rioux, Christine
中科院分区：
文献类型：
--
作者：
Brugge, Doug;Lee, Angela C;Woodin, Mark;Rioux, Christine
在欠发达国家和美国的一些新移民人口中，哮喘患病率较低，但原因尚不清楚。一种可能性是，儿童早期感染可以预防哮喘。我们调查了亚洲移民儿童（n = 204;年龄4-18），以评估哮喘与本地或外国出生地之间的关系。我们纳入了关于环境暴露、人口统计学变量和哮喘家族史的问题，以测试它们是否可以解释出生地对哮喘的影响。本地和外国出生的群体在大多数方面是相似的。分析所有年龄段与诊断哮喘的相关性，得出两个逻辑回归模型。两人均在美国出生（OR分别为3.2和4.3; p < 0.01），有哮喘家族史（OR分别为6.4和7.2; p < 0.001）。一个模型保持生活在繁忙的机动车交通附近（OR = 2.6; p = 0.012）。其他保留语言（OR = 3.2; p = 0.003）。然而，对于年龄较大的儿童（11-18岁）出生在美国失去了一些预测能力。我们的研究结果与美国以外流行的儿童早期感染一致，可以预防哮喘。
Asthma prevalence is lower in less developed countries and among some recent immigrant populations in the US, but the reasons for this are not clear. One possibility is that early childhood infections are protective against asthma. We surveyed Asian immigrant children (n = 204; age 4–18) to assess the relationship between asthma and native or foreign place of birth. We included questions about environmental exposures, demographic variables and family history of asthma to test whether they might explain effects of place of birth on asthma. The native and foreign born groups were similar in most respects. Analysis of association with diagnosed asthma for all ages together resulted in two logistic regression models. Both retained born in the US (ORs were 3.2 and 4.3; p < 0.01) and family history of asthma (ORs were 6.4 and 7.2; p < 0.001). One model retained living near heavy motor traffic (OR = 2.6; p = 0.012). The other retained language (OR = 3.2; p = 0.003). However, for older children (11–18 years of age) being born in the US lost some of its predictive power. Our findings are consistent with early childhood infections that are prevalent outside the US protecting against asthma.