Demographic characteristics of members of the Vaccine Safety Datalink (VSD): A comparison with the United States population
Demographic characteristics of members of the Vaccine Safety Datalink (VSD): A comparison with the United States population
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DOI：
10.1016/j.vaccine.2015.07.037
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发表时间：
2015-08-26
期刊：
影响因子：
5.5
通讯作者：
Gee, Julianne
中科院分区：
文献类型：
--
作者：
Sukumaran, Lakshmi;McCarthy, Natalie L.;Gee, Julianne
背景：疫苗安全数据链(VSD)是疾控中心和九个综合医疗保健系统之间的合作，是美国获得许可后疫苗安全监测的基石。考虑到参保VSD人群和美国人群之间的潜在差异可能会限制VSD研究结果的普适性，我们对两个人群的人口学特征进行了比较。方法：我们收集了2010年VSD地点的医疗记录和行政文件中的数据，将性别、年龄、种族、民族、收入和教育程度与2010年美国人口普查人口进行比较。我们还比较了2012年VSD医疗补助人口的数据和2012年美国医疗补助数据。结果：2010年VSD人口包括800多万人，占美国总人口的2.6%。所有主要人口统计组别的代表都在VSD中。我们发现，在比较VSD和美国人群的性别、种族、民族和教育程度方面，没有重大差异。中等收入人口在VSD和美国之间是相当的。虽然与美国相比，VSD的低收入人群比例较低，但VSD在这一群体中有200多万人。此外，2012年VSD中有60多万医疗补助成员，占美国医疗补助人口的1.1%。结论：我们发现VSD人口在几个关键的人口和社会经济变量上代表了美国总体人口。尽管与美国相比，VSD中的少数特定群体的代表性较低，但VSD成员的绝对数量足以确保这些群体在使用VSD数据的疫苗安全性研究中具有重要的代表性。(C)2015爱思唯尔有限公司。保留所有权利。
Background: The Vaccine Safety Datalink (VSD) is a collaboration between CDC and nine integrated health care systems that serves as a cornerstone of US post-licensure vaccine safety monitoring. Given concerns that potential differences between the insured VSD population and the US population could limit the generalizability of VSD study findings, we performed a comparison of the demographic characteristics between the two populations.Methods: We collected data from medical records and administrative files at VSD sites in 2010 to compare sex, age, race, ethnicity, income, and educational attainment to the 2010 US Census population. We also compared data on the 2012 VSD Medicaid population to 2012 US Medicaid data.Results: The VSD population included over eight million individuals in 2010, which represented 2.6% of the total US population. All major demographic groups were represented in the VSD. We found no major differences in comparing sex, race, ethnicity, and educational attainment between the VSD and the US population. Middle income populations were comparable between the VSD and the US. While the percentage of lower income populations was less in the VSD compared to the US, the VSD had over two million individuals in this group. Additionally, there were over 600,000 Medicaid members in the VSD in 2012, which represented 1.1% of the US Medicaid population.Conclusions: We found that the VSD population is representative of the general US population on several key demographic and socioeconomic variables. Despite a few specific groups being underrepresented in the VSD compared to the US, the absolute number of VSD members is large enough to ensure significant representation of these groups in vaccine safety studies that use VSD data. (C) 2015 Elsevier Ltd. All rights reserved.