Functional Imaging and Modeling of the Heart - 12th International Conference, FIMH 2023, Lyon, France, June 19-22, 2023, Proceedings
Functional Imaging and Modeling of the Heart - 12th International Conference, FIMH 2023, Lyon, France, June 19-22, 2023, Proceedings
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心脏功能成像和建模 - 第 12 届国际会议，FIMH 2023，法国里昂，2023 年 6 月 19-22 日，会议记录
DOI：
10.1007/978-3-031-35302-4_6
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Alemany I
中科院分区：
文献类型：
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作者：
Alemany I
本研究旨在通过数值模拟研究速度波动对弥散张量心血管磁共振（DT-CMR）灌注信号和张量参数的影响。考虑了振幅和频率递增的正弦速度函数和生理速度函数。这两个速度函数都用两个平均毛细管间速度分布来分析。灌注模拟的结果，连同先前的扩散结果，被用来分析灌注对扩散张量的影响。结果表明，MCSE有效补偿了研究中考虑的快速速度变化，而PGSE对速度的时间变化敏感。发现STEAM对平均毛细管间弥散的变化比对时间速度波动更敏感。这些模拟结果提供了关于分散灌注速度波动影响DT-CMR信号的可能性的见解。
The aim of this study is to investigate the impact of velocity fluctuations on the perfusion signal and tensor parameters in diffusion tensor cardiovascular magnetic resonance (DT-CMR) using numerical simulations. A sinusoidal velocity function with increasing amplitude and frequency and a physiological velocity function have been considered. Both velocity functions have been analyzed using two mean inter-capillary velocity distributions with varying levels of dispersion. The results of the perfusion simulations, along with previous diffusion results, have been utilized to analyse the impact of perfusion on the diffusion tensor. The findings indicated that MCSE effectively compensated the rapid velocity changes considered in the study, while PGSE was sensitive to temporal changes in velocity. STEAM was found to be more sensitive to variations in the mean-intercapillary dispersion rather than to temporal velocity fluctuations. These simulation results provide insights regarding the potential of dispersed perfusion velocity fluctuations to affect the DT-CMR signal.