DETERMINATION OF SOUND SPEED IN BIOLOGICAL TISSUES BASED ON FREQUENCY-ANALYSIS OF PULSE RESPONSE
DETERMINATION OF SOUND SPEED IN BIOLOGICAL TISSUES BASED ON FREQUENCY-ANALYSIS OF PULSE RESPONSE
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DOI：
10.1121/1.403897
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发表时间：
1992-09-01
影响因子：
2.4
通讯作者：
DUNN, F
中科院分区：
文献类型：
--
作者：
HACHIYA, H;OHTSUKI, S;DUNN, F
生物组织中的声速提供了重要的诊断和治疗计划信息。传统的声速测定方法通常需要换能器与试样进行物理接触，以便在时域中测量厚度和传播时间。物理接触可能导致变形并影响血流，并且时域中的传播时间的测量可能对由于组织不均匀性和表面粗糙度而导致的波形失真敏感。提出了一种用于确定声速的方法，其中在频域中估计样品中的声音传播时间和由于样品的存在而从换能器到刚性反射器的总传播时间的差，并且该方法不需要超声探头与活的或新鲜切除的组织标本的物理接触。通过对硅橡胶和丙烯酸树脂样品的声速测量，验证了该方法的有效性。在10- X 10-mm面积上测量的标准偏差小于4 m/s。猪肌肉的声速分布测量与以前发表的结果一致。
The sound speed in biological tissues provides important diagnostic and treatment planning information. Conventional methods of sound-speed determination generally require that transducers make physical contact with specimens in order to measure thickness and travel time in the time domain. The physical contact may cause deformation and affect blood flow and the measurement of travel time in the time domain may be sensitive to waveform distortion due to tissue inhomogeneity and surface roughness. A method for determination of the sound speed is proposed in which the sound travel time in the sample and the difference in total travel time from the transducer to the rigid reflector due to the presence of the sample are estimated in the frequency domain and which does not require physical contact of ultrasonic probes to living or freshly excised tissue specimens. Ultrasonic speed measurements in silicone rubber and acrylic resin specimens verified the method validity. The standard deviation of the measurements over a 10- X 10-mm area is less than 4 m/s. Sound-speed distribution measurements of porcine muscle are in agreement with previously published results.