Steroid nanocrystals prepared using the nano spray dryer B-90.
Steroid nanocrystals prepared using the nano spray dryer B-90.
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DOI：
10.3390/pharmaceutics5010107
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发表时间：
2013-01-25
期刊：
影响因子：
5.4
通讯作者：
Nishida K
中科院分区：
文献类型：
--
作者：
Baba K;Nishida K
纳米喷雾干燥器B-90为药物纳米晶体的生产提供了一种新的、简单的替代方法。在这项研究中，使用纳米喷雾干燥器B-90的类固醇纳米晶体的制备被证明。通过选择网孔尺寸来控制粒度。成功地获得了粉末形式的亚微米类固醇颗粒。使用粉末X射线衍射图案分析确认这些纳米颗粒具有晶体结构。由于药物纳米晶体最近被认为是一种新型的药物制剂的药物输送系统，这项研究将是有用的纳米医学应用。
The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicrometer steroid particles in powder form were successfully obtained. These nanoparticles were confirmed to have a crystal structure using powder X-ray diffraction pattern analysis. Since drug nanocrystals have recently been considered as a novel type of drug formulation for drug delivery systems, this study will be useful for nano-medical applications.