Work stress and low emotional support is associated with increased risk of future type 2 diabetes in women
Work stress and low emotional support is associated with increased risk of future type 2 diabetes in women
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DOI：
10.1016/j.diabres.2006.09.002
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发表时间：
2007-06-01
影响因子：
5.1
通讯作者：
Weinehall, L.
中科院分区：
文献类型：
--
作者：
Norberg, M.;Stenlund, H.;Weinehall, L.
在一项基于人群的健康调查中，一项案例参照研究调查了职业中年男性和女性的社会心理压力（如工作压力和低情感支持）与未来2型糖尿病发展之间的关系。1989-2000年期间在瑞典北部于默奥进行的一项健康调查（n = 33,336）的所有参与者都被纳入其中。我们确定了191例患者，他们最初没有糖尿病，但在5.4 +/- 2.6年后被诊断为2型糖尿病。为每个病例选择两个年龄和性别匹配的参照物。多变量logistic回归分析及变量间交互效应评价。在女性中，被动或紧张的工作环境与未来的2型糖尿病相关，比值比分别为3.6（95%置信区间1.1-11.7）和3.6(1.0-13.3)，低情感支持3.0（1.3-7.0）。这些关联在男性中没有发现。在女性中，在调整BMI、公民身份和教育水平后，他们仍然存在，并且在工作压力和低情感支持之间也存在相互作用的趋势。总之，工作压力和低情感支持可能会增加女性患2型糖尿病的风险，但对男性没有影响。这些发现有助于我们理解社会心理压力是瑞典人群中2型糖尿病的潜在危险因素。2006爱思唯尔爱尔兰有限公司版权所有。
A case-referent study nested within a population-based health survey investigated the associations between psychosocial stress, such as work stress and low emotional support, and future development of type 2 diabetes among occupationally working middle-aged men and women. All participants in a health survey conducted during 1989-2000 (n = 33,336) in Umea in northern Sweden, were included. We identified 191 cases, who were not diabetic initially but were diagnosed with type 2 diabetes after 5.4 +/- 2.6 years. Two age- and sex-matched referents were selected for each case. Multivariate logistic regression analyses and interaction effects between variables were evaluated.In women, passive or tense working situations were associated with future type 2 diabetes with odds ratios 3.6 (95% confidence interval 1.1-11.7) and 3.6 (1.0-13.3), respectively, and also low emotional support 3.0 (1.3-7.0). These associations were not seen in men. In women, they remained after adjustment for BMI, civil status and educational level, and there were also tendencies for interactions between work stress and low emotional support.In conclusion, work stress and low emotional support may increase the risk of type 2 diabetes in women, but not in men. These findings contribute to our understanding of psychosocial stress as potential risk factors for type 2 diabetes in a Swedish population. (c) 2006 Elsevier Ireland Ltd. All rights reserved.