Inflammatory breast carcinoma treated by radical radiotherapy

Inflammatory breast carcinoma treated by radical radiotherapy
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炎性乳腺癌的根治性放射治疗

DOI:
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发表时间:
1980
期刊:
影响因子:
6.2
通讯作者:
Joanne A. Doucette
Joanne A. Doucette
中科院分区:
医学1区
文献类型:
--
作者:
A. Chu;W. Wood;Joanne A. Doucette

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1960年1月至1977年12月,在马萨诸塞州总医院,对62例局部临床炎性乳腺癌患者进行了根治性乳腺放射治疗和引流。在报告时,50名患者死于疾病,7名患者仍活着,5名患者没有患病,这表明这种罕见的乳腺癌具有暴发性。中位生存期约为18个月(平均24个月)。五年精算生存率和无复发生存率分别为14%和6%。62例患者中有43例(69%)出现局部和区域复发。12例患者(19%)仅在局部照射区域失败,31例患者(50%)在局部、区域和远端部位均失败,14例患者(23%)仅因远端转移而失败。
Sixty‐two patients with localized clinical inflammatory breast carcinoma were treated with curative, radical radiotherapy doses to the breast and draining lymphatics at Massachusetts General Hospital from January 1960 to December 1977. Fifty patients have died from disease, 7 are alive with disease, and 5 are free of disease at time of reporting, thus indicating the fulminant nature of this rare form of breast cancer. Median survival is approximately 18 months (mean 24 months). A five‐year actuarial survival and relapse‐free survival of 14% and 6%, respectively, are obtained. Local and regional recurrence was noted in 43 of 62 patients (69%). Twelve patients (19%) failed in the locally irradiated area only, 31 patients (50%) failed in both local, regional, and distant sites, and 14 patients (23%) failed with distant metastases only.