Response of human pulps capped with different self-etch adhesive systems
Response of human pulps capped with different self-etch adhesive systems
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DOI：
10.1007/s00784-007-0161-9
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发表时间：
2008-06-01
影响因子：
3.4
通讯作者：
Costa, C. A. S.
中科院分区：
文献类型：
--
作者：
Accorinte, M. L. R.;Loguercio, A. D.;Costa, C. A. S.
本研究的目的是评估人类牙髓覆盖氢氧化钙硬固水泥或两步自酸蚀粘合剂系统的反应。在咬合面上进行牙髓暴露，并使用生理盐水进行出血控制。暴露的牙髓组织用Clearfil LB 2V（2V）或Clearfil SE Bond（SE）覆盖，并用复合树脂修复。对照组用Ca（OH）2水门汀盖髓，用Clearfil LB 2V或Clearfil SE Bond +复合树脂修复。在30和90天后，拔牙，进行苏木精和伊红处理，并在组织学评分系统中进行分类。在两个评价期内，当与90天时的相应对照组相比时，用自酸蚀粘合剂系统（2V和SE）覆盖的组的牙髓反应更差（p < 0.05）。对于评价的两种自酸蚀系统，牙髓组织表现出中度至重度炎性细胞浸润，涉及冠状牙髓慢性炎症。牙本质桥在少数标本中观察到。对于氢氧化钙组，几乎所有标本均显示牙本质桥形成，在牙髓暴露部位下方有少量散在的炎性细胞和正常组织。氢氧化钙应作为盖髓的首选材料，禁止使用两步自酸蚀粘合剂进行人类盖髓。
The aim of this study was to evaluate the response of human pulps capped with a calcium hydroxide hard-setting cement or with two-step self-etch adhesive systems. Pulp exposures were performed on the occlusal floor, and the bleeding control was performed with saline solution. The exposed pulp tissue was capped with Clearfil LB 2V (2V) or Clearfil SE Bond (SE) and restored with a composite resin. In control group, the pulpal wound was capped with Ca(OH)(2) cement and restored with Clearfil LB 2V or Clearfil SE Bond + composite resin. After 30 and 90 days, the teeth were extracted, processed for hematoxylin and eosin, and categorized in a histological score system. The pulpal response was worse for groups capped with the self-etch adhesive systems (2V and SE) in both periods of evaluation, when compared to their respective control groups at 90 days (p < 0.05). For both self-etch systems evaluated, the pulp tissue exhibited moderate to severe inflammatory cell infiltrate involving the coronal pulp with chronic abscesses. Dentin bridging was observed in a few specimens. For the calcium hydroxide groups, almost all specimens showed dentin bridge formation, with few scattered inflammatory cells and normal tissue below the pulp exposure site. Calcium hydroxide should be used as the material of choice for pulp capping, and the use of two-step self-etch adhesives for human pulp capping is contraindicated.