BREAST-TUMORS - COMPOSITION OF MICROCALCIFICATIONS
BREAST-TUMORS - COMPOSITION OF MICROCALCIFICATIONS
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DOI：
10.1148/radiology.169.2.2845471
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发表时间：
1988-11-01
期刊：
影响因子：
19.7
通讯作者：
TRAVERIACROS, A
中科院分区：
文献类型：
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作者：
FANDOSMORERA, A;PRATSESTEVE, M;TRAVERIACROS, A
作者研究了31例患者乳腺组织中钙化的结晶学模式，其中包括8例钙化良性病变，17例钙化癌和6例非钙化对照样本。使用扫描电子显微镜、能量色散x射线分析和带有Guinier相机的x射线衍射，得到关于乳房钙化的形状和成分的信息。多面体晶体(对钙的能量色散X射线分析响应)含有方解石、文石或草酸钙，具体取决于具体情况。草酸钙晶体仅在恶性乳腺组织中发现。球形晶体(对钙和磷的能量色散X射线分析响应)含有磷灰石。恶性过程中以球形晶体为主，但良性和恶性过程中均存在各种形态和成分。钙化与其周围组织的关系可能解释了结构上的差异，但结果尚不确定，需要进一步研究。
The authors investigated the crystallographic patterns of calcifications in breast tissue from 31 patients, including eight calcified benign lesions, 17 calcified carcinomas, and six noncalcified control samples. Scanning electron microscopy, energy-dispersive x-ray analysis, and x-ray diffraction with the Guinier camera were employed and yielded information on the shape and composition of breast calcifications. Polyhedral crystals (with energy-dispersive x-ray analysis response to calcium) contained calcite, aragonite, or calcium oxalate, depending on the case. Calcium oxalate crystals were found only in malignant breast tissues. Spherical crystals (with energy-dispersive x-ray analysis response to calcium and phosphorus) contained apatite. Spherical crystals predominated in malignant processes, but all shapes and compositions were present in both benign and malignant processes. The relationship of the calcification to its surrounding tissue may account for differences in structure, but results are inconclusive and require further study.