A glucose biosensor based on electrodeposited biocomposites of gold nanoparticles and glucose oxidase enzyme

A glucose biosensor based on electrodeposited biocomposites of gold nanoparticles and glucose oxidase enzyme
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DOI:
10.1039/b105318n
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发表时间:
2001-01-01
期刊:
影响因子:
4.2
通讯作者:
Nogami, M
Nogami, M
中科院分区:
化学2区
文献类型:
--
作者:
Bharathi, S;Nogami, M

文献摘要

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电沉积用于葡萄糖氧化酶和金纳米颗粒-硅酸盐网络在氧化铟锡(ITO)玻璃电极上的共沉积。葡萄糖氧化酶在金纳米颗粒-硅酸盐网络中的这种共包埋赋予膜生物催化活性。网络中的金纳米颗粒催化酶反应的副产物H2 O2的氧化和还原。传感器的低工作电位消除了常见干扰物的干扰,如对乙酰氨基酚、抗坏血酸、多巴胺等。
Electrodeposition was used for the codeposition of glucose oxidase enzyme and a gold nanoparticle-silicate network onto an indium tin oxide (ITO) glass electrode. This co-entrapment of glucose oxidase enzyme in a gold nanoparticle-silicate network imparts biocatalytic activity to the film. The gold nanoparticles in the network catalyse the oxidation and reduction of H2O2, the by-product of the enzymatic reaction. The low operating potential of the sensor eliminates the interference from common interferents, such as acetaminophen, ascorbic acid, dopamine, etc.