Fusarium solani: evidence for common antigenic/allergenic determinants with other Fungi Imperfecti.
Fusarium solani: evidence for common antigenic/allergenic determinants with other Fungi Imperfecti.
复制标题
茄病镰刀菌：与其他不完全真菌共同抗原/过敏决定因素的证据。
DOI：
10.1111/j.1365-2222.1987.tb02330.x
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Lehrer,SB
中科院分区：
文献类型：
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作者：
O'Neil,CE;Reed,MA;Hughes,JM;Butcher,BT;Lehrer,SB
Aqueous extracts ofFusarium solaniand other members of the Fungi Imperfecti were evaluated for the presence of common antigenic/allergenic determinants using skin‐prick testing, radio‐allergo‐sorbent test (RAST) inhibition, and immunoelectrophoretic methods. Prevalence of skin reactivity in forty‐four atopic individuals, tested with commercially available fungal extracts, ranged from 27.3% forAlternaria tenuisto 6.8% forPenicillium notatum.No specific patterns of reactivity emerged from statistical analyses of skin test data. In contrast, RAST inhibition demonstrated common allergenic determinants.P. notatumandAspergillus glaucusinhibitedF. solaniRAST by 79% and 84%, respectively. This was supported by crossed line immunoelectrophoresis; bothP. notatumandA. glaucushad antigenic determinants in common withF. solani.Collectively, these studies suggest thatF. solani, P. notatum, andA. glaucushave several common antigenic/allergenic determinants.
