Unclassified subtype of Guillain-Barre syndrome is associated with quick recovery.
Unclassified subtype of Guillain-Barre syndrome is associated with quick recovery.
复制标题
格林-巴利综合征的未分类亚型与快速恢复有关。
DOI：
10.1016/j.jocn.2021.07.025
复制
发表时间：
2021
期刊：
影响因子：
2
通讯作者：
Adachi H.
中科院分区：
文献类型：
--
作者：
Ohnari K;Okada K;Mafune K;Kusunoki S;Adachi H.
格林-巴利综合征(GBS)的电生理分类对预测其临床病程具有重要意义，但很少有报道讨论不符合急性炎症性脱髓鞘性多发性神经病(AIDP)或急性运动轴突性神经病(AMAN)分类的GBS患者。因此，本研究评估了未分类的GBS的特征，并将其与AIDP和AMAN进行了比较。根据Rajabally、Hadden和Ho制定的标准，我们比较了AIDP、AMAN和未分类的GBS亚型患者的临床症状、神经传导和实验室数据。根据Rajabally标准，未分类亚组上肢和下肢F波频率高于AIDP和AMAN亚组，而根据Hadden和Ho标准，未分类亚组仅下肢F波频率高于其他亚组。未分类亚组按Rajabally标准预后较好。Rajabally标准分型有助于判断GBS患者的预后和确定治疗方案。此外，未分类的患者表现出最快的恢复。
Electrophysiological classification of Guillain-Barré syndrome (GBS) is important for predicting its clinical course; however, few reports discuss GBS patients who do not conform to the acute inflammatory demyelinating polyneuropathy (AIDP) or acute motor axonal neuropathy (AMAN) classifications. Therefore, the present study assessed the features of unclassified types of GBS and compared them to those of AIDP and AMAN. We compared clinical symptoms, nerve conduction, and laboratory data among patients with AIDP, AMAN, and unclassified subtypes of GBS, according to criteria developed by Rajabally, Hadden, and Ho. According to the Rajabally criteria, the F wave frequency in the upper and lower extremities was higher in the unclassified subgroup than in the AIDP and AMAN subgroups; however, according to the Hadden and Ho criteria, the F wave frequency in only the lower extremities was higher in the unclassified subgroup than in the other subgroups. The unclassified subgroup showed better prognosis using the Rajabally criteria. Classification with the Rajabally criteria is useful for predicting prognosis and determining treatment in patients with GBS. Moreover, unclassified patients exhibit the quickest recovery.