Meta-analytical study of productive and nutritional interactions of mycotoxins in broilers
Meta-analytical study of productive and nutritional interactions of mycotoxins in broilers
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DOI：
10.3382/ps.2011-01470
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发表时间：
2011-09-01
期刊：
影响因子：
4.4
通讯作者：
Lovatto, P. A.
中科院分区：
文献类型：
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作者：
Andretta, I.;Kipper, M.;Lovatto, P. A.
本研究采用Meta分析方法，对霉菌毒素与肉鸡生产性能、生产指标和器官重量的关系进行了研究。使用了1980年至2009年期间发表的98篇论文，共计1，401种饮食和37，371只动物。荟萃分析遵循3个序贯分析：图形分析、相关分析和方差-协方差分析。与对照组相比，日粮中霉菌毒素的存在使采食量降低12%（P <0.05），增重降低14%（P <0.05）。赭曲霉毒素和黄曲霉毒素是对采食量和鸟类生长影响最大的真菌毒素，分别使采食量减少17%和11%，体重增加分别减少20%和11%（P <0.05）。饲料中的霉菌毒素浓度和攻毒时的动物年龄是进一步提高估计霉菌毒素对体重增加影响的方程的决定系数的变量。霉菌毒素对幼禽生长的影响更大。残差分析表明，65%的体重增加的变化是由饲料摄入量。与非攻毒肉鸡相比，攻毒肉鸡的增重变化也受到蛋白质和蛋氨酸等营养素摄入的影响。在接受脱氧雪腐镰刀菌烯醇和黄曲霉毒素饮食的组中，死亡率分别高8.8和2.8倍（P <0.05）。霉菌毒素还使肝脏的相对重量增加了15%，肾脏增加了11%，肺增加了9%，砂囊增加了3%（P <0.05）。霉菌毒素影响肉鸡的生产性能、生产指数和器官重量。然而，影响的程度因霉菌毒素的类型和浓度、动物年龄和营养因素而异。
A meta-analysis was carried out to study the association of mycotoxins with performance, productive indices, and organ weights in broilers. Ninety-eight papers published between 1980 and 2009 were used, totaling 1,401 diets and 37,371 animals. Meta-analysis followed 3 sequential analyses: graphical, correlation, and variance-covariance. The mycotoxin presence in diets reduced (P < 0.05) feed intake by 12% and weight gain by 14% compared with control group. Ochratoxins and aflatoxins were the mycotoxins with the greatest effect on feed intake and bird growth, reducing (P < 0.05) feed ingestion by 17 and 11%, respectively, and weight gain by 20 and 11%, respectively. The mycotoxin concentration in diets and the animal age at challenge were the variables that more improved the coefficient of determination for equations to estimate mycotoxin effect on weight gain. The mycotoxin effect on growth proved to be greater in young poultry. The residual analysis revealed that 65% of the variation in weight gain was explained by feed intake. The variation in weight gain of challenged broilers in relation to nonchallenged broilers was also influenced by ingestion of nutrients such as protein and methionine. Mortality was 8.8 and 2.8 times greater (P < 0.05) in groups that received diets with deoxynivalenol and aflatoxins, respectively. Mycotoxins also increased (P < 0.05) the relative weight of liver by 15%, of kidneys by 11%, of lungs by 9%, and of gizzard by 3%. Mycotoxins influenced broiler performance, productive indices, and organ weights. However, the magnitude of the effects varied with type and concentration of mycotoxin, animal age, and nutritional factors.