Crystalline arrays of membrane-bound acetylcholine receptor.
Crystalline arrays of membrane-bound acetylcholine receptor.
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膜结合乙酰胆碱受体的晶体阵列。
DOI：
10.1073/pnas.78.6.3678
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发表时间：
1981
影响因子：
11.1
通讯作者：
Stroud,RM
中科院分区：
文献类型：
--
作者：
Kistler,J;Stroud,RM
电子显微照片与膜结合乙酰胆碱受体低聚物的结晶排列已分析了数字图像重建。受体分子是向突触外定向的，在投影中它们似乎是不对称的，并且有一个明确的方向。免疫电镜显示，所有四个亚基都包含在低聚物中；因此，这些结构似乎适合于低聚物的亚基定位。
Electron micrographs of tubular structures with a crystalline arrangement of membrane-bound acetylcholine receptor oligomers have been analyzed by digital image reconstruction. The receptor molecules are oriented synaptic side out, and in projection they appear to be asymmetric and have a defined orientation. All four subunits are contained in the oligomers as demonstrated by immunoelectron microscopy; these structures therefore appear to be suitable for subunit localization in the oligomer.