Correlations of functional capacity and neuropsychological performance in older patients with schizophrenia: Evidence for specificity of relationships?

Correlations of functional capacity and neuropsychological performance in older patients with schizophrenia: Evidence for specificity of relationships?
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DOI:
10.1016/j.schres.2006.07.024
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发表时间:
2007-01-01
影响因子:
4.5
通讯作者:
Harvey, Philip D.
Harvey, Philip D.
中科院分区:
医学2区
文献类型:
--
作者:
McClure, Margaret M.;Bowie, Christopher R.;Harvey, Philip D.

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背景资料:神经心理学(NP)表现是精神分裂症患者日常功能的一致相关性,但目前尚不清楚个人NP能力领域和日常功能领域之间的关系是一般的还是具体的。对现实世界日常功能的评估可能会受到环境和社会因素的影响(例如,社会保障、残疾状况、生活条件中的机会和限制)。本研究探讨了不同的NP能力和性能为基础的措施的社会和生活skills.Methods:181门诊老年(年龄> 50)精神分裂症患者之间的关系的特异性进行了检查,NP测试测量情节和工作记忆,执行功能,言语流畅性,和处理速度。所有受试者进行任务检查社会(社会技能表现评估:SSPA)和日常生活(UCSD基于性能的技能评估:UPSA)skills.Results:使用典型分析,NP变量被用来预测的功能能力措施。分析发现,功能能力和NP测量的37%的方差是共享的,X-2(54)= 106.29,p
Background: Neuropsychological (NP) performance is a consistent correlate of everyday functioning in schizophrenia, but it is unclear whether relationships between individual NP ability areas and domains of everyday functioning are general or specific. Assessments of real-world everyday functioning may be influenced by environmental and social factors (e.g., social security, disability status, opportunities and restrictions in living situations). This study examined the specificity of the relationships between different NP abilities and performance-based measures of social and living skills.Methods: 181 ambulatory older (age > 50) patients with schizophrenia were examined with NP tests measuring episodic and working memory, executive functioning, verbal fluency, and processing speed. All subjects performed tasks examining social (Social Skills Performance Assessment: SSPA) and everyday living (UCSD Performance Based Skills Assessment: UPSA) skills.Results: Using canonical analysis, the NP variables were used to predict the functional capacity measures. The analysis found that 37% of the variance in the functional capacity and NP measures was shared, X-2 (54) = 106.29, p