The map-based sequence of the rice genome
The map-based sequence of the rice genome
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DOI：
10.1038/nature03895
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发表时间：
2005-08-11
期刊：
影响因子：
64.8
通讯作者：
Sugiura, M
中科院分区：
文献类型：
--
作者：
Matsumoto, T;Wu, JZ;Sugiura, M
水稻是世界上最重要的粮食作物之一，与其他禾本科植物有着重要的同线关系，是禾本科植物的模式植物。在这里，我们提出了一个基于地图的，完成的质量序列，覆盖95%的389 Mb的基因组，包括几乎所有的常染色质和两个完整的着丝粒。共鉴定了37，544个非转座元件相关蛋白编码基因，其中71%在拟南芥中具有推定的同源物。在相互分析中，90%的拟南芥蛋白质在预测的水稻蛋白质组中具有推定的同源物。在37,544个预测基因中，有29%出现在聚类基因家族中。在水稻基因组中发现的转座因子的数量和种类与玉米和高粱基因组中同线区域的扩展是一致的。我们发现广泛和经常性的基因转移的细胞器的核染色体的证据。基于图位的序列已被证明可用于鉴定农艺性状的基因。在我们的研究中发现的额外的单核苷酸多态性和简单重复序列应该加速水稻产量的提高。
Rice, one of the world's most important food plants, has important syntenic relationships with the other cereal species and is a model plant for the grasses. Here we present a map-based, finished quality sequence that covers 95% of the 389 Mb genome, including virtually all of the euchromatin and two complete centromeres. A total of 37,544 non-transposable-element-related protein-coding genes were identified, of which 71% had a putative homologue in Arabidopsis. In a reciprocal analysis, 90% of the Arabidopsis proteins had a putative homologue in the predicted rice proteome. Twenty-nine per cent of the 37,544 predicted genes appear in clustered gene families. The number and classes of transposable elements found in the rice genome are consistent with the expansion of syntenic regions in the maize and sorghum genomes. We find evidence for widespread and recurrent gene transfer from the organelles to the nuclear chromosomes. The map-based sequence has proven useful for the identification of genes underlying agronomic traits. The additional single-nucleotide polymorphisms and simple sequence repeats identified in our study should accelerate improvements in rice production.