Bone structure and geometry in young men: The influence of smoking, alcohol intake and physical activity
Bone structure and geometry in young men: The influence of smoking, alcohol intake and physical activity
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DOI：
10.1016/j.bone.2012.09.003
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发表时间：
2013-01-01
期刊：
影响因子：
4.1
通讯作者：
Montgomery, Hugh E.
中科院分区：
文献类型：
--
作者：
Eleftheriou, Kyriacos I.;Rawal, Jaikirty S.;Montgomery, Hugh E.
背景资料：骨质疏松症的发展受到青年时期达到的峰值骨量的影响-生活方式因素对骨质疏松症的影响描述不多，尤其是在男性中。方法：对723名健康男性新兵（平均值+/- S.E.）进行髋关节骨密度（双能X线吸收法，DXA）、骨微结构（跟骨定量超声，QUS）和股骨几何结构（磁共振成像，MRI）的研究。年龄19.92 +/- 0.09岁[范围16-18岁]，身高177.67 +/- 0.24 cm，体重73.17 +/- 0.37 kg）。协会寻求与先前的体力活动，吸烟状况和酒精intake.Results：DXA的措施，在650，MRI措施，在572新兵QUS措施。增加负重体力活动水平可增强骨膜骨沉积，增加全髋和股骨颈骨矿物质密度（BMD; p
Background: The development of osteoporosis is influenced by peak bone mass attained in youth - the influence of lifestyle factors upon which is poorly described, especially amongst males. We sought to address this issue in a large scale study.Methods: Hip bone mineral density (dual X-ray absorptiometry, DXA), bone microarchitecture (calcaneal quantitative ultrasound, QUS) and femoral geometry (magnetic resonance imaging, MRI) were characterised in 723 healthy male military recruits (mean +/- S.E. age 19.92 +/- 0.09 years [range 16-18 years], height 177.67 +/- 0.24 cm, weight 73.17 +/- 0.37 kg) on entry to UK Army training. Association was sought with prior physical activity, smoking status and alcohol intake.Results: DXA measures were made in 651, MRI measures in 650, and QUS measures in 572 recruits. Increasing levels of weight-bearing physical activity enhanced periostial bone apposition, increases in both total hip and femoral neck bone mineral density (BMD; p