Transit time corrected arterial spin labeling technique aids to overcome delayed transit time effect
Transit time corrected arterial spin labeling technique aids to overcome delayed transit time effect
复制标题
通过时间校正的动脉自旋标记技术有助于克服延迟通过时间效应
DOI：
10.1007/s00234-017-1969-x
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发表时间：
2018
期刊：
影响因子：
2.8
通讯作者：
R. Lebel
中科院分区：
文献类型：
--
作者：
T. Yun;T. Yun;C. Sohn;C. Sohn;Roh;Roh;Koung Mi Kang;Koung Mi Kang;S. Choi;S. Choi;Ji Hoon Kim;Ji Hoon Kim;Sun;M. Hwang;R. Lebel
本研究旨在评价基于多时相动脉自旋标记磁共振灌注成像(ASL-MRP)的渡越时间校正脑血流量(CBF)图的应用价值。书面知情同意被放弃。108例患者行常规及多时相ASL-MRP和动态磁化率增强磁共振灌注成像(DSC-MRP)。将基于血管区域的感兴趣体积应用于从DSC-MRP获得的CBF和峰值时间(TTP)图，以及从常规和多时相ASL-MRP获得的CBF图。用Bland-Altman分析评价DSC-MRP的归一化CBF(NCBF)与常规CBF图和多时相ASL-MRP的过渡时间校正CBF图的一致性。结果常规和多时相ASL-MRP的nCBF值均低于Δ-MRP的nCBF值(均值分别为0.08和0.07)。ASLnCBF值依赖于常规Δ- = 技术的TTP值(F = 5.5679，P = 0.0384)。Δ脑血流量与多时相ASLMRP的TTP值无相关性(F = 0.1433，P >； 0.0 5)。结论基于多时相ASLMRP的传递时间校正脑血流图可克服传递时间延迟对常规ASLMRP灌注图的影响。
PurposeThis study aimed to evaluate the usefulness of transit time corrected cerebral blood flow (CBF) maps based on multi-phase arterial spin labeling MR perfusion imaging (ASL-MRP).MethodsThe Institutional Review Board of our hospital approved this retrospective study. Written informed consent was waived. Conventional and multi-phase ASL-MRPs and dynamic susceptibility contrast MR perfusion imaging (DSC-MRP) were acquired for 108 consecutive patients. Vascular territory-based volumes of interest were applied to CBF and time to peak (TTP) maps obtained from DSC-MRP and CBF maps obtained from conventional and multi-phase ASL-MRPs. The concordances between normalized CBF (nCBF) from DSC-MRP and nCBF from conventional and transition time corrected CBF maps from multi-phase ASL-MRP were evaluated using Bland-Altman analysis. In addition, the dependence of difference between nCBF (ΔnCBF) values obtained from DSC-MRP and conventional ASL-MRP (or multi-phase ASL-MRP) on TTP obtained from DSC-MRP was also analyzed using regression analysis.ResultsThe values of nCBFs from conventional and multi-phase ASL-MRPs had lower values than nCBF based on DSC-MRP (mean differences, 0.08 and 0.07, respectively). The values of ΔnCBF were dependent on TTP values from conventional ASL-MRP technique (F = 5.5679, P = 0.0384). No dependency of ΔnCBF on TTP values from multi-phase ASL-MRP technique was revealed (F = 0.1433, P > 0.05).ConclusionThe use of transit time corrected CBF maps based on multi-phase ASL-MRP technique can overcome the effect of delayed transit time on perfusion maps based on conventional ASL-MRP.
DOI：
10.1016/j.mric.2009.01.008
发表时间：
2009-05
影响因子：
1.6
作者：
Pollock, Jeffrey M.;Tan, Huan;Kraft, Robert A.;Whitlow, Christopher T.;Burdette, Jonathan H.;Maldjian, Joseph A.
通讯作者：
Maldjian, Joseph A.