Variation in mobility and exercise adaptations between Drosophila species
Variation in mobility and exercise adaptations between Drosophila species
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DOI：
10.1007/s00359-020-01421-x
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发表时间：
2020-04-25
影响因子：
2.1
通讯作者：
Wessells, Robert
中科院分区：
文献类型：
--
作者：
Cobb, Tyler;Sujkowski, Alyson;Wessells, Robert
运动和流动性已被广泛研究，在果蝇，但很少知道其他果蝇物种的运动能力，而在其他物种的慢性运动的反应还有待检查。结果表明，成年雄性D.黑腹果蝇适应运动训练，与未运动的果蝇相比，具有改善的跑步耐力、攀爬速度和飞行能力。在这里，我们检查基线流动性的D。sechellia，D. simulans和D.以及他们对慢性运动训练的反应。我们发现显着种间差异的流动性和运动的反应。虽然在运动适应上存在显著的性别差异，但在运动适应上，D.黑腹果蝇，种内分析显示，在其他果蝇物种的性别差异很少。由于章鱼胺对D.对于黑腹鼠，我们还询问是否任何观察到的差异可归因于基线章鱼胺水平。我们发现，章鱼胺和酪胺水平有相同的排名顺序为基线攀登速度和耐力的男性，但不预测长期运动的男性或女性的反应。未来的研究应侧重于确定的机制负责间和种内的差异，在流动性和运动的反应。
Locomotion and mobility have been studied extensively in Drosophila melanogaster but less is known about the locomotor capacity of other Drosophila species, while the response to chronic exercise in other species has yet to be examined. We have shown that adult male D. melanogaster adapt to exercise training with improved running endurance, climbing speed, and flight ability compared to unexercised flies. Here, we examine baseline mobility of D. sechellia, D. simulans, and D. virilis, and their response to chronic exercise training. We found significant interspecific differences in mobility and in the response to exercise. Although there is a significant sex difference in exercise adaptations in D. melanogaster, intraspecific analysis reveals few sex differences in other Drosophila species. As octopamine has been shown to be important for exercise adaptations in D. melanogaster, we also asked if any observed differences could be attributed to baseline octopamine levels. We find that octopamine and tyramine levels have the same rank order as baseline climbing speed and endurance in males, but do not predict the response to chronic exercise in males or females. Future research should focus on determining the mechanisms responsible for the inter- and intraspecific differences in mobility and the response to exercise.