Deoxyribonucleic Acid Antibody: A Method to Detect Its Primary Interaction with Deoxyribonucleic Acid
Deoxyribonucleic Acid Antibody: A Method to Detect Its Primary Interaction with Deoxyribonucleic Acid
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脱氧核糖核酸抗体：检测其与脱氧核糖核酸主要相互作用的方法
DOI：
10.1126/science.161.3843.806
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发表时间：
1968
期刊：
影响因子：
56.9
通讯作者：
R. Farr
中科院分区：
文献类型：
--
作者：
R. T. Wold;F. Young;E. Tan;R. Farr
硫酸铵法可检测人血清中DNA抗体。这种敏感和特异的技术，测量DNA和DNA抗体之间的主要相互作用，是基于观察到游离DNA可溶于50%饱和硫酸铵，而抗体结合的DNA是不溶的。
Antibody to DNA in human serums can be detected by the ammonium sulfate method. This sensitive and specific technique, which measures the primary interaction between DNA and antibody to DNA, is based on the observation that free DNA is soluble in 50-percent saturated ammonium sulfate whereas antibody-bound DNA is insoluble.