ALCOHOL AND MORTALITY: A U-SHAPED CURVE
ALCOHOL AND MORTALITY: A U-SHAPED CURVE
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酒精与死亡率：U 形曲线
DOI：
10.1016/s0140-6736(81)92032-8
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Briony J. Thomas
中科院分区：
文献类型：
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作者：
M. Marmot;M. Marmot;G. Rose;G. Rose;M. Shipley;M. Shipley;Briony J. Thomas;Briony J. Thomas
在一项针对公务员的纵向研究中，根据平均每日饮酒量对 1422 名男性进行了分类。经过 10 年的随访，报告适度饮酒的男性死亡率低于不饮酒者或大量饮酒者（每天酒精 >34 克）。不饮酒者的心血管死亡率较高，饮酒较多者的非心血管死亡率较高。酗酒者的平均血压较高，吸烟者的比例也较高。多变量分析显示，报告的饮酒量与随后的死亡率之间的这种 U 形关系在很大程度上与吸烟、血压、血浆胆固醇和就业等级的差异无关。
In a longitudinal study of civil servants, 1422 men were classified according to their average daily alcohol intake. Over 10 years of follow-up, the mortality rate was lower in men reporting moderate alcohol intake than in either non-drinkers or heavier drinkers (>34 g alcohol per day). Cardiovascular mortality was greater in non-drinkers and non-cardiovascular mortality was greater in the heavier drinkers. The heavier drinkers had higher mean blood pressures and contained a greater proportion of smokers. A multivariate analysis showed this U-shaped relationship between reported alcohol consumption and subsequent mortality to be largely independent of differences in smoking, blood pressure, plasma cholesterol, and grade of employment.