Pulmonary rehabilitation improves depression, anxiety, dyspnea and health status in patients with COPD
Pulmonary rehabilitation improves depression, anxiety, dyspnea and health status in patients with COPD
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DOI：
10.1097/phm.0b013e31802b8eca
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发表时间：
2007-01-01
影响因子：
3
通讯作者：
Celli, Bartolome R.
中科院分区：
文献类型：
--
作者：
Paz-Diaz, Hildegarde;De Oca, Maria Montes;Celli, Bartolome R.
目的：探讨8周综合肺康复方案对慢性阻塞性肺疾病(COPD)患者抑郁、焦虑、呼吸困难及健康相关生活质量的影响。设计：将24例重度COPD患者随机分为肺康复组(PR组，n=10)和对照组(C组，n=14；FEV1组，FEV1组34+/-11%)。公关计划包括疾病教育、节能技术、放松和锻炼，包括20分钟的哑铃抬臂和20分钟的腿部锻炼，每周三次，持续8周。结果：PR后患者抑郁程度明显改善(P<；0.01)，症状减轻(P<；0.05)，日常生活活动能力增强(P<；0.05)，SGRQ总分下降(P<；0.01)。在呼吸困难方面，PR组明显优于PR组(P<；0.01)。结论：本研究表明，在重度COPD患者中，肺康复治疗可引起抑郁和焦虑的重要改变，而不依赖于呼吸困难和健康相关生活质量的改变。
Objective: To determine the impact of an 8-wk program of comprehensive pulmonary rehabilitation on depression, anxiety, dyspnea, and health-related quality of life in patients with chronic obstructive pulmonary disease (COPD).Design: We studied 24 patients with severe COPD randomized either to pulmonary rehabilitation (PR), (n = 10; FEV1 30 +/- 9%) or control (C; n = 14; FEV1 34 +/- 11%). The PR program included disease education, energy conservation techniques, relaxation, and exercise including 20-min arm elevation with dumbbells and 20-min leg exercise sessions three times a week for 8 wks. At baseline and after completion of the program, all patients were evaluated using the Beck Depression Inventory, State Trait Anxiety Inventory (STAI), Modified Medical Research Council Scale (MRC), and St. George's Respiratory Questionnaire (SGRQ).Results: After PR, there was a significant improvement in the severity of depression (P < 0.01), a decrease in symptoms (P < 0.05), an increase in daily living activities (P < 0.05), and a decrease in the total score of the SGRQ (P < 0.01). Dyspnea measured by the MRC scale was significantly better in the PR group (P < 0.01).Conclusions: The present study shows that in patients with severe COPD, pulmonary rehabilitation induces important changes on depression and anxiety independent of changes in dyspnea and health-related quality-of-life.