Failure to detect dopamine receptor IgG autoantibodies in sera of schizophrenic patients

Failure to detect dopamine receptor IgG autoantibodies in sera of schizophrenic patients
复制标题

精神分裂症患者血清中多巴胺受体 IgG 自身抗体检测失败

DOI:
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发表时间:
2005
影响因子:
3.3
通讯作者:
H. Kornhuber
H. Kornhuber
中科院分区:
医学3区
文献类型:
--
作者:
A. V. Kirchbach;E. Fischer;H. Kornhuber

文献摘要

被引文献

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已经假设精神分裂症患者体内存在针对多巴胺受体的自身抗体。从 15 名精神分裂症急性发作患者 (DSM III) 的血清中分离出 IgG。然而,3H-螺哌酮与多巴胺受体的结合并未被该级分抑制。
Autoantibodies against dopamine receptors in schizophrenic patients have been postulated. IgG was fractionated from sera of 15 schizophrenic patients (DSM III) in an acute episode. However, 3H-spiperone binding to dopamine receptors was not inhibited by this fraction.