Safety of influenza vaccinations administered in nontraditional settings
Safety of influenza vaccinations administered in nontraditional settings
复制标题
DOI：
10.1016/j.vaccine.2005.09.061
复制
发表时间：
2006-05-01
期刊：
影响因子：
5.5
通讯作者：
Nichol, Kristin L.
中科院分区：
文献类型：
--
作者：
D'Heilly, Sarah J.;Blade, Mary Ann;Nichol, Kristin L.
非传统环境（NTS）越来越多地用于成人疫苗接种，但其安全性存在担忧。我们对在明尼苏达州NTS接种疫苗的542，445人进行了这项分析，以评估NTS流感疫苗接种的安全性。共报告了112起不良事件（AE），95起为即刻事件，17起为晚期事件。大多数AE为轻度，并在几分钟内消退。63人（0.01%）对疫苗接种有血管迷走神经反应，22人（0.004%）报告了注射部位问题。速发型超敏反应非常罕见，仅10例（0.002%）疫苗接种者出现需要肾上腺素治疗的速发型反应。15例（0.003%）患者因AE需要在急诊室或医生办公室接受评价。未报告死亡。我们的结论是，流感疫苗接种在大规模疫苗接种诊所是安全的，流感疫苗接种后的不良事件在NTS是非常低的。爱思唯尔有限公司出版
Nontraditional settings (NTS) are increasingly utilized for adult vaccination but concerns exist about their safety. We conducted this analysis of 542,445 persons vaccinated at an NTS in Minnesota to assess the safety of influenza vaccination in NTS. A total of 112 adverse events (AEs) were reported, 95 immediate and 17 late. Most AEs were mild and resolved within several minutes. 63 persons (.01%) had a vasovagal reaction to vaccination and 22 (.004%) reported an injection site problem. Immediate hypersensitivity reactions were very rare with only 10 (.002%) vaccine recipients having an immediate reaction for which epinephrine was required. Fifteen (.003%) individuals required evaluation in an emergency room or physician's office because of an AE. No deaths were reported. We conclude that influenza vaccine administration in mass vaccination clinics is safe and adverse events after influenza vaccination in NTS are extremely low. Published by Elsevier Ltd.