Ethnic differences in the hemodynamic mechanisms of ambulatory blood pressure regulation.

Ethnic differences in the hemodynamic mechanisms of ambulatory blood pressure regulation.
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动态血压调节的血流动力学机制存在种族差异。

DOI:
10.1016/s0895-7061(02)03269-7
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发表时间:
2003
影响因子:
3.2
通讯作者:
McFetridge,Judy
McFetridge,Judy
中科院分区:
医学3区
文献类型:
--
作者:
Sherwood,Andrew;Hughes,JoelW;McFetridge,Judy

文献摘要

被引文献

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背景非洲裔美国人通常比白人表现出更大的全身血管阻力(SVR),以应对实验室挑战,导致血压(BP)升高。然而,动态血压调节(ABP)的种族差异尚未被检验。方法我们监测了10名非洲裔美国人和10名白人男女的ABP。动态心阻抗监测在每个ABP读数的同时评估心输出量和SVR。结果我们发现SVR是非裔美国人(P<.01)每日ABP变化的显著预测因子,但在白人中不是。结论在日常活动中,对于非裔美国人来说,SVR可能比白人在调节ABP方面发挥更显著的作用。Am J Hyperten 2003;16:270-273@2003美国高血压杂志有限公司
BackgroundAfrican Americans typically exhibit greater systemic vascular resistance (SVR) than do white individuals in response to laboratory challenges that raise blood pressure (BP). However, ethnic differences in ambulatory blood pressure (ABP) regulation have not been examined.MethodsWe monitored ABP in a sample of 10 African American and 10 white men and women. Ambulatory cardiac impedance monitoring was used to assess cardiac output and SVR concurrently with each ABP reading.ResultsWe found that SVR was a significant predictor of daily ABP variations in African Americans (P< .01) but not in whites.ConclusionFor African Americans, SVR may play a more prominent role than for whites in the regulation of ABP during routine daily activities. Am J Hypertens 2003;16: 270–273 @ 2003 American Journal of Hypertension, Ltd.