GENETIC-ANALYSIS OF INSTABILITY IN PETUNIA-HYBRIDA .1. A HIGHLY UNSTABLE MUTATION INDUCED BY A TRANSPOSABLE ELEMENT INSERTED AT THE ANL LOCUS FOR FLOWER COLOR
GENETIC-ANALYSIS OF INSTABILITY IN PETUNIA-HYBRIDA .1. A HIGHLY UNSTABLE MUTATION INDUCED BY A TRANSPOSABLE ELEMENT INSERTED AT THE ANL LOCUS FOR FLOWER COLOR
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DOI：
10.1007/bf00272873
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发表时间：
1984-01-01
影响因子：
5.4
通讯作者：
BIANCHI, F
中科院分区：
文献类型：
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作者：
DOODEMAN, M;BOERSMA, EA;BIANCHI, F
提出了一种假说来解释杂交杨不稳定突变体的杂交试验结果，这些突变体的花朵斑驳，花冠的颜色强度和斑点程度也发生了变化。参与花青素合成的An1基因座可能由一个结构基因和一个相邻的调控区组成，后者又由两个组成部分组成，突变子负责结构基因的激活，表达子负责控制活性速率。不稳定的ANL等位基因源于插入在调节区内的转座元件引起的缺失。这样的缺失从插入元件的一端延伸到相邻的DNA上，因此可能包括部分表达子和突变子。反转是由缺失的修复导致的，插入的元素不一定在该过程中丢失。
A hypothesis is proposed to interpret the results of crossing experiments with unstable mutants of P. hybrida having variegated flowers and showing variation in the color intensity and the degree of spotting of the corolla. The An1 locus, which is involved in anthocyanin synthesis, is probably composed of a structural gene with an adjoining regulatory region, the latter in turn comprising 2 components, the mutator, responsible for the activation of the structural gene, and the expressor, controlling the rate of activity. Unstable Anl alleles originate from deletions induced by a transposable element inserted within the regulatory region. Such deletions extend from one of the ends of the inserted element across the adjacent DNA and thus may include parts of the expressor and the mutator. Reversions result from repair of the deletions, the inserted element not necessarily becoming lost in the process.