GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus
GABAergic circuitry in the dorsal division of the cat medial geniculate nucleus
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DOI：
10.1002/cne.10387
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发表时间：
2002-11-04
影响因子：
2.5
通讯作者：
Schofield, BR
中科院分区：
文献类型：
--
作者：
Coomes, DL;Bickford, ME;Schofield, BR
γ-氨基丁酸（GABA）是丘脑的主要抑制性神经递质。我们使用植入后免疫细胞化学研究猫内侧膝状体核（MGN）背侧浅亚部GABA阳性的突触组织。三组GABA阳性的配置文件参与突触：轴突终末，树突和突触前树突。突触前GABA阳性终末主要靶向GABA阴性树突。GABA阳性突触后轮廓主要从GABA阴性轴突接收输入。结果表明，GABA阳性分布在MGN核背侧浅亚部的突触组织是非常相似的，在丘脑其他核。(C)2002 Wiley-Liss，Inc.
gamma-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the thalamus. We used postembedding immunocytochemistry to examine the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the cat medial geniculate nucleus (MGN). Three groups of GABA-positive profiles participate in synapses: axon terminals, dendrites, and presynaptic dendrites. The presynaptic GABA-positive terminals target mainly GABA-negative dendrites. The GABA-positive postsynaptic profiles receive input primarily from GABA-negative axons. The results indicate that the synaptic organization of GABA-positive profiles in the dorsal superficial subdivision of the MGN nucleus is very similar to that in other thalamic nuclei. (C) 2002 Wiley-Liss, Inc.