Enhancement of Non-Invasive Recording of Electroenterogram by Means of a Flexible Array of Concentric Ring Electrodes
Enhancement of Non-Invasive Recording of Electroenterogram by Means of a Flexible Array of Concentric Ring Electrodes
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DOI：
10.1007/s10439-013-0935-y
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发表时间：
2014-03-01
影响因子：
3.8
通讯作者：
Ye-Lin, Y.
中科院分区：
文献类型：
--
作者：
Garcia-Casado, J.;Zena-Gimenez, V.;Ye-Lin, Y.
通过肠电图（EEnG）监测肠肌电活动对于诊断胃肠道病变和疾病具有重要的临床意义。然而，表面EEnG记录具有非常低的振幅，并且可能受到基线漂移以及呼吸和心电图（ECG）干扰的严重影响。在这项工作中，一个灵活的同心环电极阵列的开发和测试，以确定它是否可以提供更好的质量比双极记录从传统的圆盘电极的表面EEnG信号。为此，16名健康受试者在空腹状态下（>8小时）进行记录。研究了该系统检测肠道起搏活动（慢波）的能力及生理干扰的影响。从同心环电极获得的信号被证明是更强大的心电图和呼吸干扰比传统的圆盘电极。结果还表明，肠道EEnG组件，如慢波可以更容易地识别所提出的系统的基础上的一个灵活的同心环电极阵列。所开发的有源电极阵列可能是一个非常有价值的工具，用于非侵入性诊断疾病状态，如缺血和运动障碍的小肠，这是已知的改变正常的肠道慢波活动。
Monitoring intestinal myoelectrical activity by electroenterogram (EEnG) would be of great clinical interest for diagnosing gastrointestinal pathologies and disorders. However, surface EEnG recordings are of very low amplitude and can be severely affected by baseline drifts and respiratory and electrocardiographic (ECG) interference. In this work, a flexible array of concentric ring electrodes was developed and tested to determine whether it can provide surface EEnG signals of better quality than bipolar recordings from conventional disc electrodes. With this aim, sixteen healthy subjects in a fasting state (>8 h) underwent recording. The capability of detecting intestinal pacemaker activity (slow wave) and the influence of physiological interferences were studied. The signals obtained from the concentric ring electrodes proved to be more robust toECGand respiratory interference than those from conventional disc electrodes. The results also show that intestinal EEnG components such as the slow wave can be more easily identified by the proposed system based on a flexible array of concentric ring electrodes. The developed active electrode array could be a very valuable tool for non-invasive diagnosis of disease states such as ischemia and motility disorders of the small bowel which are known to alter the normal enteric slow wave activity.