Synovitis of the wrist caused by Mycobacterium florentinum
Synovitis of the wrist caused by Mycobacterium florentinum
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弗洛伦分枝杆菌引起的手腕滑膜炎
DOI：
10.1007/s15010-013-0561-5
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发表时间：
2014
期刊：
影响因子：
7.5
通讯作者：
Yoko Nukui
中科院分区：
文献类型：
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作者：
Yoko Nukui
弗洛伦蒂诺分枝杆菌是一种新发现的、罕见的、生长缓慢的非结核分枝杆菌（NTM）。在此，我们报告一例m。日本1例免疫功能低下患者弗洛伦丁诱发的手腕滑膜炎。通过对therpoB、hsp65和16S rRNA基因的序列分析鉴定了弗洛伦丁菌。他们。本研究中的florentinumstrain无法与某些m。hsp65或16S rRNA序列，因为它们偶尔有超过99%的序列相同。isolatedM。florentinum菌株仅对克拉霉素和阿米卡星敏感。最初，患者给予克拉霉素、左氧氟沙星和乙胺丁醇治疗，然后给予克拉霉素、左氧氟沙星和利福平治疗。据我们所知，M。弗洛伦丁诱发的滑膜炎以前未见报道。我们的研究结果表明，除了其他已知的致病性NTM外，最近发现的m。Florentinumstrain应被认为是滑膜炎的可能原因。此外，我们在识别m时应该谨慎。弗洛伦蒂诺，因为这个菌株非常类似于m。triplexin基因型。
Mycobacterium florentinumis a newly identified, rare, slow-growing species of nontuberculous mycobacteria (NTM). Here, we report a case ofM. florentinum-induced synovitis of the wrist in an immunocompromised Japanese patient.M. florentinumwas identified by sequence analysis of therpoB,hsp65, and 16S rRNA genes. TheM. florentinumstrain in this study could not be differentiated from certainM. triplexstrains by thehsp65or 16S rRNA sequences alone, because they occasionally shared more than 99 % sequence identity. The isolatedM. florentinumstrain was only susceptible to clarithromycin and amikacin. Initially, the patient was treated with clarithromycin, levofloxacin, and ethambutol, and then with clarithromycin, levofloxacin, and rifampicin. To our knowledge,M. florentinum-induced synovitis has not been previously reported. Our results suggest that, in addition to other well-known pathogenic NTM, the recently identifiedM. florentinumstrain should be considered as a possible cause of synovitis. Moreover, we should be cautious when identifyingM. florentinumbecause this strain closely resemblesM. triplexin genotype.