Colonic metastasis from breast carcinoma: a case report
Colonic metastasis from breast carcinoma: a case report
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DOI：
10.1186/s12957-017-1193-5
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发表时间：
2017-07-05
影响因子：
3.2
通讯作者：
Shiroma, Hiroshi
中科院分区：
文献类型：
--
作者：
Tsujimura, Kazuma;Teruya, Tsuyoshi;Shiroma, Hiroshi
背景：乳腺癌结肠转移非常罕见。现报道一例乳腺癌结肠转移病例。病例介绍：患者，女，51岁。她反复出现上腹部疼痛、呕吐和腹泻。我们进行了腹部对比增强计算机断层扫描 (CT) 来调查这些症状。 CT 扫描显示升结肠有肿瘤，对比增强，小肠扩张。为了进一步研究该肿瘤，我们进行了全正电子发射断层扫描-计算机断层扫描（PET-CT）。 PET-CT 扫描显示升结肠、肠系膜、左乳房和左腋窝区域有氟脱氧葡萄糖摄取。对结肠镜检查期间获得的活检样本的分析显示出印戒细胞样癌。此外，乳腺肿瘤活检显示浸润性小叶癌。因此，术前诊断为乳腺癌结肠转移。进行开放性回盲部切除术。最终诊断为多发性转移性乳腺癌，TNM分期为T2N1M1 IV期。结论：我们报道了罕见的乳腺癌结肠转移病例。 PET-CT 可能有助于诊断转移性乳腺癌。当结肠镜检查期间获得的活检样本分析显示印戒细胞样癌时，应考虑乳腺癌作为原发肿瘤的可能性。
Background: Colonic metastasis from breast carcinoma is very rare. Here, we report a case of colonic metastasis from breast carcinoma.Case presentation: The patient was a 51-year-old woman. She had upper abdominal pain, vomiting, and diarrhea, repeatedly. We performed abdominal contrast-enhanced computed tomography (CT) to investigate these symptoms. The CT scan revealed a tumor in the ascending colon with contrast enhancement and showed an expanded small intestine. For further investigation of this tumor, we performed whole positron emission tomography-computed tomography (PET-CT). The PET-CT scan revealed fluorodeoxyglucose uptake in the ascending colon, mesentery, left breast, and left axillary region. Analysis of biopsy samples obtained during colonoscopy revealed signet ring cell-like carcinoma. Moreover, biopsy of the breast tumor revealed invasive lobular carcinoma. Therefore, the preoperative diagnosis was colonic metastasis from breast carcinoma. Open ileocecal resection was performed. The final diagnosis was multiple metastatic breast carcinomas, and the TNM classification was T2N1M1 Stage IV.Conclusions: We presented a rare case of colonic metastasis from breast carcinoma. PET-CT may be useful in the diagnosis of metastatic breast cancer. When analysis of biopsy samples obtained during colonoscopy reveals signet ring cell-like carcinoma, the possibility of breast cancer as the primary tumor should be considered.