Unidirectional migration of single smooth muscle cells under the synergetic effects of gradient swelling cue and parallel groove patterns
Unidirectional migration of single smooth muscle cells under the synergetic effects of gradient swelling cue and parallel groove patterns
复制标题
梯度膨胀线索和平行凹槽模式协同作用下单个平滑肌细胞的单向迁移
DOI：
10.1016/j.colsurfb.2013.05.011
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发表时间：
2013-11-01
影响因子：
5.8
通讯作者：
Gao, Changyou
中科院分区：
文献类型：
--
作者：
Han, Lulu;Mao, Zhengwei;Gao, Changyou
空气等离子体处理的聚（二甲基硅氧烷）膜与线性槽和脊交替组装聚（4-苯乙烯磺酸钠）（PSS）/聚（二烯丙基二甲基铵）氯化物（PDADMAC）多层膜，然后在3-5 M NaCl的梯度溶液中处理，图案方向平行于梯度。表面形貌和溶胀梯度的协同作用可以有效地引导单个平滑肌细胞的单向迁移而不损害其迁移速率。(C)2013爱思唯尔有限公司版权所有。
The air-plasma treated poly(dimethylsiloxane) membrane with linear grooves and ridges is alternately assembled with poly(sodium 4-styrenesulfonate) (PSS)/poly(diallyldimethylammonium) chloride (PDADMAC) multilayers, which is then treated in a gradient solution of 3-5 M NaCl, with the pattern direction parallel to the gradient. The synergetic effects of the surface topography and swelling gradient can effectively guide the unidirectional migration of single smooth muscle cells without impairment of their migration rate. (C) 2013 Elsevier B.V. All rights reserved.