Treatment of chronic sialadenitis by intraductal penicillin or saline

Treatment of chronic sialadenitis by intraductal penicillin or saline
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DOI:
10.1016/j.joms.2003.07.007
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发表时间:
2004-04-01
影响因子:
1.9
通讯作者:
Papanayotou, P
Papanayotou, P
中科院分区:
医学4区
文献类型:
--
作者:
Antoniades, D;Harrison, JD;Papanayotou, P

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目的:我们试图描述导管内青霉素或生理盐水治疗慢性唾液腺炎。 患者和方法:研究组包括 32 名男性和 23 名女性,年龄 12 至 65 岁,患有慢性颌下唾液腺炎,以及 16 名男性和 11 名女性,年龄 8 至 65 岁,患有慢性腮腺炎,接受青霉素或生理盐水导管内滴注治疗。结果:颌下唾液腺炎患者中,青霉素治疗44例,生理盐水治疗11例,症状消失。 3 例接受青霉素治疗后症状复发,其中 2 例在进一步滴注后症状消失,1 例在去除导管口处的唾液石后症状消失;对22名患者的随访证实,18名接受青霉素治疗的患者和4名接受生理盐水治疗的患者分别在1至15年和1至3年内没有症状。在腮腺炎患者中,18 名接受青霉素治疗的患者、8 名接受生理盐水治疗的患者以及 1 名同时接受两者治疗的患者症状消失; 1 名接受青霉素治疗的患者和 1 名接受生理盐水治疗的患者再次出现症状,两人在进一步滴注后症状均消失;对 15 名患者的随访证实,11 名接受青霉素治疗、3 名接受生理盐水治疗、1 名同时接受两种治疗的患者分别在 1 至 14 年、2 至 12 年和 3 年无症状。 结论:导管内滴注青霉素或生理盐水是治疗慢性唾液腺炎的一种简单且令人惊讶的成功技术。 (C) 2004 年美国口腔颌面外科医师协会。
Purpose: We sought to describe the treatment of chronic sialadenitis by intraductal penicillin or saline.Patients and Methods: The study group consisted of 32 males and 23 females with chronic submandibular sialadenitis aged 12 to 65 years and 16 males and 11 females with chronic parotitis aged 8 to 65 years who were treated by intraductal instillation of penicillin or saline.Results: in the patients with submandibular sialadenitis, 44 patients treated with penicillin and 11 treated with saline became symptom free; symptoms recurred in 3 treated with penicillin, of whom 2 became symptom free after further instillations and 1 after removal of a sialolith at the ductal orifice; and follow-up of 22 patients verified that 18 treated with penicillin and 4 with saline had been symptom free for 1 to 15 years and 1 to 3 years, respectively. In the patients with parotitis, 18 patients treated with penicillin, 8 treated with saline, and 1 treated with both became symptom free; symptoms recurred in 1 treated with penicillin and 1 with saline, both of whom became symptom free after further instillations; and follow-up of 15 patients verified that 11 treated with penicillin, 3 with saline, and 1 with both had been symptom free for 1 to 14 years, 2 to 12 years, and 3 years, respectively.Conclusion: The intraductal instillation of penicillin or saline is a simple and surprisingly successful technique for the treatment of chronic sialadenitis. (C) 2004 American Association of Oral and Maxillofacial Surgeons.