Selective inactivation of human immunodeficiency virus with subpicosecond near-infrared laser pulses
Selective inactivation of human immunodeficiency virus with subpicosecond near-infrared laser pulses
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DOI：
10.1088/0953-8984/20/25/252205
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发表时间：
2008-06-25
影响因子：
2.7
通讯作者：
Kiang, Juliann G.
中科院分区：
文献类型：
--
作者：
Tsen, K. T.;Tsen, Shaw-Wei D.;Kiang, Juliann G.
We demonstrate for the first time that human immunodeficiency virus (HIV) can be inactivated by irradiation with subpicosecond near-infrared laser pulses at a moderate laser power density. By comparing the threshold laser power density for the inactivation of HIV with those of human red blood cells and mouse dendritic cells, we conclude that it is plausible to use the ultrashort pulsed laser to selectively inactivate blood-borne pathogens such as HIV while leaving sensitive materials like human red blood cells unharmed. This finding has important implications in the development of a new laser technology for disinfection of viral pathogens in blood products and in the clinic.
