Photobiomodulation by a 635nm Diode Laser on Peri-Implant Bone: Primary and Secondary Stability and Bone Density Analysis-A Randomized Clinical Trial
Photobiomodulation by a 635nm Diode Laser on Peri-Implant Bone: Primary and Secondary Stability and Bone Density Analysis-A Randomized Clinical Trial
复制标题
DOI：
10.1155/2019/2785302
复制
发表时间：
2019-01-01
影响因子：
--
通讯作者：
Romeo, Umberto
中科院分区：
文献类型：
--
作者：
Matys, Jacek;Swider, Katarzyna;Romeo, Umberto
导论.牙科种植学中的各种程序被执行以增强骨愈合过程和种植体稳定性。这些方法之一可以是低水平激光治疗（LLLT）。目标.本研究的目的是评价使用635 nm半导体激光进行LLLT方案后种植体周围区域的稳定性（初级和次级）和骨密度。材料和方法。该研究包括24名患者（8名女性和16名男性;年龄：46.7 +/- 8.7岁）的下颌骨后部区域放置的40个种植体。将患者随机分为2组，G1组（n=12，18个植入物）和G2（n=12，22个植入物）根据治疗程序; G1（试验）：635 nm激光，手柄直径：8 mm，输出功率：100 mW，光斑面积：0.5024 cm（2），平均功率密度：199.04 mW/cm（2），连续模式，剂量：4J/点（8 J/cm（2）），时间：40秒/点，2个点（照射牙槽/种植体的颊侧和舌侧），每次总能量8 J; G2（对照）：无激光照射。根据以下方案对G1（试验）组的植入物进行辐照：术前1天、术后即刻以及术后2、4、7和14天。所有治疗疗程后的总能量为48 J。使用Periotest装置测量种植体稳定性（Periotest测试值：PTV）（术后即刻、术后7天、2周、4周、2个月和3个月测量），并使用锥形束计算机断层扫描（灰度值）测量骨密度（术后即刻、治疗后4周和12周测量）。结果与对照组（G2）相比，635 nm激光照射（G1）后第2周和第4周，不同时间点的平均植入物稳定性显示PTV值较低（稳定性较高）（p <0.05）。钛种植体顶部、中部和颈部水平的平均灰度值显示2周后像素灰度值降低，并且G1组低于G2组（p
Introduction. Various procedures in dental implantology are performed to enhance the bone healing process and implant stability. One of these methods can be a low-level laser therapy (LLLT). Objectives. The aim of our study was to evaluate the stabilization (primary and secondary) and bone density in peri-implant zone after LLLT protocol using a 635 nm diode laser. Material and Methods. The research included 40 implants placed in the posterior region of a mandible in 24 patients (8 women and 16 man; age: 46.7 +/- 8.7 years). The patients were randomly divided into 2 groups G1 (n=12, 18 implants) and G2 (n=12, 22 implants) according to the treatment procedure; G1 (test): 635 nm laser, with handpiece diameter: 8mm, output power: 100mW, spot area: 0.5024cm(2), average power density: 199.04mW/cm(2), continuous mode, dose: 4J per point (8J/cm(2)), time: 40 sec per point, 2 points (irradiation on a buccal and a lingual side of the alveolus/implant), and total energy per session 8J; G2 (control): no laser irradiation. The G1 (test) group's implants were irradiated according to the following protocol: 1 day before surgery, immediately after the surgery and 2, 4, 7, and 14 days after. The total energy after all therapeutic sessions was 48J. The implants stability was measured employing a Periotest device (Periotest Test Value: PTV) (measured immediately after the surgery, 7 days, 2 weeks, 4 weeks, and 2 and 3 months after the surgery) and the bone density using cone-beam computed tomography (grayscale value) (measured immediately after the surgery, 4 weeks and 12 weeks after the treatment). Results. The average implant stability at different time points showed lower PTV value (higher stability) at 2nd and 4th week after 635 nm laser irradiation (G1) compared with a control (G2) group (p0.05). The mean grayscale value at the apical, middle, and cervical level of the titanium implants showed the reduction of pixel grayscale value after 2 weeks and was lower for the G1 group in contrast to the G2 group (p