Electric Charge Dependence of Controlled Dye-Release Behavior in Glass Ionomer Cement Containing Nano-Porous Silica Particles
Electric Charge Dependence of Controlled Dye-Release Behavior in Glass Ionomer Cement Containing Nano-Porous Silica Particles
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DOI：
10.1166/jnn.2018.14618
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发表时间：
2018-01-01
影响因子：
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通讯作者：
Iida, Junichiro
中科院分区：
文献类型：
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作者：
Bando, Yosuke;Nakanishi, Ko;Iida, Junichiro
我们研究了含有纳米空腔的纳米二氧化硅颗粒（纳米多孔二氧化硅，NPS）的受控染料释放行为。为了确定这一点，将 NPS 与玻璃离子水门汀 (GIC) 混合，玻璃离子水门汀是一种用作基质的医用材料。使用紫外可见分光光度计观察染料释放行为。将阳离子染料装入含有 NPS 的 GIC 颗粒后，颗粒可以在长达两周的时间内逐渐释放阳离子染料。为了了解电荷对染料释放行为的依赖性，还研究了三种具有不同电荷的染料。具有中性或负电荷的染料在几天内迅速从颗粒中释放出来。这些结果表明，NPS 中存在的纳米腔可以选择性地结合阳离子染料并允许其逐渐释放。这一结果揭示了NPS优异的持续染料释放性能。
We investigated in controlled dye-release behavior of nanosized silica particles containing nanocavities (Nanoporous silica, NPS). To determine this, NPS were mixed with glass ionomer cement (GIC), which is a medical material used as a matrix. The dye-release behavior was observed using a UV-visible spectrometer. After cationic dye was charged into GIC pellet containing NPS, the pellet could gradually release cationic dye for up to two weeks. To understand the dependence of electric charge on the dye-release behavior, three types of dyes with different charge were also investigated. Dyes having a neutral or negative electric charge were quickly released from the pellet within a couple of days. These results suggest that the nanocavities present in NPS can selectively bind cationic dyes and allow for their gradual release. This result reveals the excellent sustained dye-release property of NPS.