Innervation of human atrioventricular and arterial valves
Innervation of human atrioventricular and arterial valves
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DOI：
10.1161/01.cir.94.3.368
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发表时间：
1996-08-01
期刊：
影响因子：
37.8
通讯作者：
Wharton, J
中科院分区：
文献类型：
--
作者：
Marron, K;Yacoub, MH;Wharton, J
关于人类心脏瓣膜的神经支配以及神经纤维和末梢与小叶内元素的关系的信息有限。方法和结果我们使用定量免疫组织化学、组织化学和共聚焦显微镜技术检测了人死后和手术中获得的AV和动脉瓣膜。心脏瓣膜之间和瓣膜内的神经密度和分布均有显著差异。例如，二尖瓣前叶的神经密度是后叶的两倍(P
Background Limited information exists on the innervation of human cardiac valves and the relationship of nerve fibres and terminals with elements within leaflets.Methods and Results We examined human AV and arterial valves, obtained postmortem and at surgery, using quantitative immunohistochemical, histochemical, and confocal microscopic techniques. Significant differences in nerve density and distribution were found both between and within cardiac valves. Nerve density within the anterior leaflet of the mitral valve, for example, was twofold greater than that in the posterior leaflet (P