The lymphatic system in body homeostasis: physiological conditions.
The lymphatic system in body homeostasis: physiological conditions.
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DOI：
10.1089/15396850360495655
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发表时间：
2003-01-01
影响因子：
1.4
通讯作者：
Olszewski, Waldemar L
中科院分区：
文献类型：
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作者：
Olszewski, Waldemar L
淋巴系统是一个有组织的网络，由功能上相互关联的淋巴组织以及组织液/淋巴和淋巴细胞的运输通路组成。其主要组成部分包括：1. 迁移的树突状细胞、巨噬细胞和淋巴细胞，有组织的淋巴组织，如淋巴结、胸腺、脾脏、骨髓以及肠道和肺部的淋巴组织、肝脏淋巴细胞以及非淋巴器官的树突状细胞网络；2. 血管（细胞间隙、淋巴管和血管周围间隙）；3. 液体（组织液和淋巴）。淋巴系统可分为以下部分：外周部分（从组织间隙到最近的淋巴结及其内部）和中枢部分（传出淋巴管、乳糜池和胸导管，所有淋巴器官）。淋巴系统传入支最活跃的器官和组织是皮肤、肠道和肺部。这些是暴露于外界环境的身体结构。所有其他非淋巴身体组织也有组织液/淋巴渗透，并包含树突状细胞和巨噬细胞网络。文中介绍了从正常人体获取的有关淋巴成分和流量的数据。还概述了淋巴研究的未来趋势。
The lymphatic system is an organized network composed of functionally interrelated lymphoid tissue, and transportation pathways of tissue fluid/lymph and lymphoid cells. Its main components are 1. migrating dendritic cells, macrophages and lymphocytes, organized lymphoid tissue such as lymph nodes, thymus, spleen, bone marrow, and lymphoid tissue in gut and lungs, liver lymphoid cells, and the dendritic cell network of nonlymphoid organs; 2. vessels (intercellular space, lymphatics, and perivascular spaces); 3. fluids (tissue fluid and lymph). The lymphatic system can be divided into the following compartments: peripheral (from the interstitial space to and within the nearest lymph node), and central (efferent lymphatics, cysterna chyli, and thoracic duct, all lymphoid organs). Organs and tissues with the most active afferent arm of the lymphatic system are skin, gut, and lungs. These are the body structures exposed to the external environment. All other nonlymphoid bodily tissues are also percolated by tissue fluid/lymph, and contain a network of dendritic cells and macrophages. Data obtained from normal human subjects on lymph composition and flow are presented. Future trends in lymphatic research are outlined.